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49 results

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Page 1
Immunotherapeutic targeting of surfaceome heterogeneity in AML.
Bordeleau ME, Audemard É, Métois A, Theret L, Lisi V, Farah A, Spinella JF, Chagraoui J, Moujaber O, Aubert L, Khakipoor B, Mallinger L, Boivin I, Mayotte N, Hajmirza A, Bonneil É, Béliveau F, Pfammatter S, Feghaly A, Boucher G, Gendron P, Thibault P, Barabé F, Lemieux S, Richard-Carpentier G, Hébert J, Lavallée VP, Roux PP, Sauvageau G. Bordeleau ME, et al. Among authors: chagraoui j. Cell Rep. 2024 Jun 25;43(6):114260. doi: 10.1016/j.celrep.2024.114260. Epub 2024 Jun 4. Cell Rep. 2024. PMID: 38838225 Free article.
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Fares I, et al. Among authors: chagraoui j. Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337. Science. 2014. PMID: 25237102 Free PMC article.
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard É, Thibault P, Bonneil É, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith MA, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm BT, Cellot S. Gress V, et al. Among authors: chagraoui j. Blood Adv. 2024 Jan 9;8(1):112-129. doi: 10.1182/bloodadvances.2022008899. Blood Adv. 2024. PMID: 37729615 Free PMC article.
IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia.
Métois A, Bordeleau ME, Theret L, Hajmirza A, Moujaber O, Spinella JF, Chagraoui J, Mayotte N, Boivin I, Audemard É, Aubert L, Lisi V, Khakipoor B, Farah A, Bonneil É, Robert A, Lippens J, Moraitis A, Béliveau F, Feghaly A, Boucher G, Marcotte R, Gendron P, Thibault P, Lemieux S, Richard-Carpentier G, Lavallée VP, Hébert J, Roux PP, Sauvageau G. Métois A, et al. Among authors: chagraoui j. Biomark Res. 2025 Apr 14;13(1):61. doi: 10.1186/s40364-025-00769-z. Biomark Res. 2025. PMID: 40229904 Free PMC article.
CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy.
Lehnertz B, Langouët M, Corneau S, MacRae T, Joe M, Schmidt EN, Spinella JF, Mayotte N, Moore S, Tellechea MF, Boivin I, Papineau L, Rojas-Sutterlin S, Tual M, Cortes CJ, Chagraoui J, Tomellini E, Desse V, Gagnon E, Macauley MS, Sauvageau G. Lehnertz B, et al. Among authors: chagraoui j. Mol Ther. 2026 Feb 4;34(2):1047-1065. doi: 10.1016/j.ymthe.2025.11.010. Epub 2025 Nov 10. Mol Ther. 2026. PMID: 41220177
DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.
Moison C, Mendoza-Sanchez R, Gracias D, Schuetz DA, Spinella JF, Girard S, Thavonekham B, Chagraoui J, Durand A, Fortier S, MacRae T, Bonneil E, Rose Y, Mayotte N, Boivin I, Thibault P, Hébert J, Ruel R, Marinier A, Sauvageau G. Moison C, et al. Among authors: chagraoui j. EMBO Rep. 2025 Jun;26(11):2836-2854. doi: 10.1038/s44319-025-00448-y. Epub 2025 Apr 28. EMBO Rep. 2025. PMID: 40295725 Free PMC article.
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.
Cohen S, Roy J, Lachance S, Delisle JS, Marinier A, Busque L, Roy DC, Barabé F, Ahmad I, Bambace N, Bernard L, Kiss T, Bouchard P, Caudrelier P, Landais S, Larochelle F, Chagraoui J, Lehnertz B, Corneau S, Tomellini E, van Kampen JJA, Cornelissen JJ, Dumont-Lagacé M, Tanguay M, Li Q, Lemieux S, Zandstra PW, Sauvageau G. Cohen S, et al. Among authors: chagraoui j. Lancet Haematol. 2020 Feb;7(2):e134-e145. doi: 10.1016/S2352-3026(19)30202-9. Epub 2019 Nov 6. Lancet Haematol. 2020. PMID: 31704264 Clinical Trial.
49 results