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Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour.
Charlton J, Williams RD, Sebire NJ, Popov S, Vujanic G, Chagtai T, Alcaide-German M, Morris T, Butcher LM, Guilhamon P, Beck S, Pritchard-Jones K. Charlton J, et al. Among authors: chagtai t. Genome Med. 2015 Feb 2;7(1):11. doi: 10.1186/s13073-015-0136-4. eCollection 2015. Genome Med. 2015. PMID: 25763109 Free PMC article.
Bilateral wilms tumor with TP53-related anaplasia.
Popov SD, Vujanic GM, Sebire NJ, Chagtai T, Williams R, Vaidya S, Pritchard-Jones K. Popov SD, et al. Among authors: chagtai t. Pediatr Dev Pathol. 2013 May-Jun;16(3):217-23. doi: 10.2350/12-08-1245-CR.1. Epub 2013 Feb 6. Pediatr Dev Pathol. 2013. PMID: 23387809
Multiple mechanisms of MYCN dysregulation in Wilms tumour.
Williams RD, Chagtai T, Alcaide-German M, Apps J, Wegert J, Popov S, Vujanic G, van Tinteren H, van den Heuvel-Eibrink MM, Kool M, de Kraker J, Gisselsson D, Graf N, Gessler M, Pritchard-Jones K. Williams RD, et al. Among authors: chagtai t. Oncotarget. 2015 Mar 30;6(9):7232-43. doi: 10.18632/oncotarget.3377. Oncotarget. 2015. PMID: 25749049 Free PMC article.
Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications.
Cresswell GD, Apps JR, Chagtai T, Mifsud B, Bentley CC, Maschietto M, Popov SD, Weeks ME, Olsen ØE, Sebire NJ, Pritchard-Jones K, Luscombe NM, Williams RD, Mifsud W. Cresswell GD, et al. Among authors: chagtai t. EBioMedicine. 2016 Jul;9:120-129. doi: 10.1016/j.ebiom.2016.05.029. Epub 2016 May 27. EBioMedicine. 2016. PMID: 27333041 Free PMC article.
Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms' tumor.
Williams RD, Al-Saadi R, Chagtai T, Popov S, Messahel B, Sebire N, Gessler M, Wegert J, Graf N, Leuschner I, Hubank M, Jones C, Vujanic G, Pritchard-Jones K; Children's Cancer and Leukaemia Group; SIOP Wilms' Tumour Biology Group. Williams RD, et al. Among authors: chagtai t. Clin Cancer Res. 2010 Apr 1;16(7):2036-45. doi: 10.1158/1078-0432.CCR-09-2890. Epub 2010 Mar 23. Clin Cancer Res. 2010. PMID: 20332316 Free PMC article.
Gain of 1q As a Prognostic Biomarker in Wilms Tumors (WTs) Treated With Preoperative Chemotherapy in the International Society of Paediatric Oncology (SIOP) WT 2001 Trial: A SIOP Renal Tumours Biology Consortium Study.
Chagtai T, Zill C, Dainese L, Wegert J, Savola S, Popov S, Mifsud W, Vujanić G, Sebire N, Le Bouc Y, Ambros PF, Kager L, O'Sullivan MJ, Blaise A, Bergeron C, Mengelbier LH, Gisselsson D, Kool M, Tytgat GA, van den Heuvel-Eibrink MM, Graf N, van Tinteren H, Coulomb A, Gessler M, Williams RD, Pritchard-Jones K. Chagtai T, et al. J Clin Oncol. 2016 Sep 10;34(26):3195-203. doi: 10.1200/JCO.2015.66.0001. Epub 2016 Jul 18. J Clin Oncol. 2016. PMID: 27432915 Free PMC article. Clinical Trial.
Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in Wilms tumor.
Williams RD, Al-Saadi R, Natrajan R, Mackay A, Chagtai T, Little S, Hing SN, Fenwick K, Ashworth A, Grundy P, Anderson JR, Dome JS, Perlman EJ, Jones C, Pritchard-Jones K. Williams RD, et al. Among authors: chagtai t. Genes Chromosomes Cancer. 2011 Dec;50(12):982-95. doi: 10.1002/gcc.20907. Epub 2011 Aug 31. Genes Chromosomes Cancer. 2011. PMID: 21882282
14 results