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Interaction and stimulation of human FEN-1 nuclease activities by heterogeneous nuclear ribonucleoprotein A1 in alpha-segment processing during Okazaki fragment maturation.
Chai Q, Zheng L, Zhou M, Turchi JJ, Shen B. Chai Q, et al. Biochemistry. 2003 Dec 30;42(51):15045-52. doi: 10.1021/bi035364t. Biochemistry. 2003. PMID: 14690413
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks.
Zheng L, Zhou M, Chai Q, Parrish J, Xue D, Patrick SM, Turchi JJ, Yannone SM, Chen D, Shen B. Zheng L, et al. EMBO Rep. 2005 Jan;6(1):83-9. doi: 10.1038/sj.embor.7400313. EMBO Rep. 2005. PMID: 15592449 Free PMC article.
Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC. Chai Q, et al. Nature. 2006 Dec 21;444(7122):1096-100. doi: 10.1038/nature05411. Epub 2006 Dec 13. Nature. 2006. PMID: 17167418
Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies.
Froning KJ, Leaver-Fay A, Wu X, Phan S, Gao L, Huang F, Pustilnik A, Bacica M, Houlihan K, Chai Q, Fitchett JR, Hendle J, Kuhlman B, Demarest SJ. Froning KJ, et al. Protein Sci. 2017 Oct;26(10):2021-2038. doi: 10.1002/pro.3240. Epub 2017 Jul 31. Protein Sci. 2017. PMID: 28726352 Free PMC article.
Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy.
Wu J, Schultz JS, Weldon CL, Sule SV, Chai Q, Geng SB, Dickinson CD, Tessier PM. Wu J, et al. Protein Eng Des Sel. 2015 Oct;28(10):403-14. doi: 10.1093/protein/gzv045. Epub 2015 Sep 12. Protein Eng Des Sel. 2015. PMID: 26363633
Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease.
Benschop RJ, Chow CK, Tian Y, Nelson J, Barmettler B, Atwell S, Clawson D, Chai Q, Jones B, Fitchett J, Torgerson S, Ji Y, Bina H, Hu N, Ghanem M, Manetta J, Wroblewski VJ, Lu J, Allan BW. Benschop RJ, et al. MAbs. 2019 Aug/Sep;11(6):1175-1190. doi: 10.1080/19420862.2019.1624463. Epub 2019 Jun 10. MAbs. 2019. PMID: 31181988 Free PMC article.
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