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31 results
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Nonadherent cells switch to a Rac-mediated, SHIP regulated, Akt activation mode for survival.
Chaigne-Delalande B, Anies G, Kramer I, Genot E. Chaigne-Delalande B, et al. Oncogene. 2008 Mar 20;27(13):1876-85. doi: 10.1038/sj.onc.1210830. Epub 2007 Oct 1. Oncogene. 2008. PMID: 17906692
CD95 engagement mediates actin-independent and -dependent apoptotic signals.
Chaigne-Delalande B, Mahfouf W, Daburon S, Moreau JF, Legembre P. Chaigne-Delalande B, et al. Cell Death Differ. 2009 Dec;16(12):1654-64. doi: 10.1038/cdd.2009.111. Epub 2009 Aug 14. Cell Death Differ. 2009. PMID: 19680267
Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway.
Bénéteau M, Pizon M, Chaigne-Delalande B, Daburon S, Moreau P, De Giorgi F, Ichas F, Rebillard A, Dimanche-Boitrel MT, Taupin JL, Moreau JF, Legembre P. Bénéteau M, et al. Mol Cancer Res. 2008 Apr;6(4):604-13. doi: 10.1158/1541-7786.MCR-07-0331. Mol Cancer Res. 2008. PMID: 18403639
The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.
Guidicelli G, Chaigne-Delalande B, Dilhuydy MS, Pinson B, Mahfouf W, Pasquet JM, Mahon FX, Pourquier P, Moreau JF, Legembre P. Guidicelli G, et al. PLoS One. 2009;4(5):e5493. doi: 10.1371/journal.pone.0005493. Epub 2009 May 11. PLoS One. 2009. PMID: 19430526 Free PMC article.
The immunosuppressor mycophenolic acid kills activated lymphocytes by inducing a nonclassical actin-dependent necrotic signal.
Chaigne-Delalande B, Guidicelli G, Couzi L, Merville P, Mahfouf W, Bouchet S, Molimard M, Pinson B, Moreau JF, Legembre P. Chaigne-Delalande B, et al. J Immunol. 2008 Dec 1;181(11):7630-8. doi: 10.4049/jimmunol.181.11.7630. J Immunol. 2008. PMID: 19017951
Actin-independent exclusion of CD95 by PI3K/AKT signalling: implications for apoptosis.
Pizon M, Rampanarivo H, Tauzin S, Chaigne-Delalande B, Daburon S, Castroviejo M, Moreau P, Moreau JF, Legembre P. Pizon M, et al. Eur J Immunol. 2011 Aug;41(8):2368-78. doi: 10.1002/eji.201041078. Epub 2011 Jul 4. Eur J Immunol. 2011. PMID: 21557211
Rewinding the DISC.
Chaigne-Delalande B, Moreau JF, Legembre P. Chaigne-Delalande B, et al. Arch Immunol Ther Exp (Warsz). 2008 Jan-Feb;56(1):9-14. doi: 10.1007/s00005-008-0002-9. Epub 2008 Feb 5. Arch Immunol Ther Exp (Warsz). 2008. PMID: 18250974 Review.
Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.
Duplomb L, Chaigne-Delalande B, Vusio P, Raher S, Jacques Y, Godard A, Blanchard F. Duplomb L, et al. Endocrinology. 2003 Dec;144(12):5381-9. doi: 10.1210/en.2003-0607. Epub 2003 Aug 28. Endocrinology. 2003. PMID: 12959977
The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.
Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P. Tauzin S, et al. PLoS Biol. 2011 Jun;9(6):e1001090. doi: 10.1371/journal.pbio.1001090. Epub 2011 Jun 21. PLoS Biol. 2011. PMID: 21713032 Free PMC article.
CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. Khadra N, et al. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19072-7. doi: 10.1073/pnas.1116946108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065776 Free PMC article.
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