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The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.
Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. Thompson KN, et al. Among authors: chakrabarti kr. Oncotarget. 2015 Nov 3;6(34):35231-46. doi: 10.18632/oncotarget.6159. Oncotarget. 2015. PMID: 26497685 Free PMC article.
SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.
Feng Y, Pan TC, Pant DK, Chakrabarti KR, Alvarez JV, Ruth JR, Chodosh LA. Feng Y, et al. Among authors: chakrabarti kr. Cancer Discov. 2014 Jul;4(7):790-803. doi: 10.1158/2159-8290.CD-13-0548. Epub 2014 Apr 30. Cancer Discov. 2014. PMID: 24786206 Free PMC article.
154 results