Chakrabarty P - Search Results

1

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Ada… See abstract for full author list ➔ Sims R, et al. Among authors: chakrabarty p. Nat Genet. 2017 Sep;49(9):1373-1384. doi: 10.1038/ng.3916. Epub 2017 Jul 17. Nat Genet. 2017. PMID: 28714976 Free PMC article.

2

Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy.

Das P, Smithson LA, Price RW, Holloway VM, Levites Y, Chakrabarty P, Golde TE. Das P, et al. Among authors: chakrabarty p. J Neuroinflammation. 2006 Jul 26;3:17. doi: 10.1186/1742-2094-3-17. J Neuroinflammation. 2006. PMID: 16872492 Free PMC article.

3

IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.

Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P. Chakrabarty P, et al. J Immunol. 2010 May 1;184(9):5333-43. doi: 10.4049/jimmunol.0903382. Epub 2010 Apr 5. J Immunol. 2010. PMID: 20368278 Free PMC article.

4

Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo.

Chakrabarty P, Herring A, Ceballos-Diaz C, Das P, Golde TE. Chakrabarty P, et al. Mol Neurodegener. 2011 Feb 16;6:16. doi: 10.1186/1750-1326-6-16. Mol Neurodegener. 2011. PMID: 21324189 Free PMC article.

5

Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification.

Chakrabarty P, Ceballos-Diaz C, Lin WL, Beccard A, Jansen-West K, McFarland NR, Janus C, Dickson D, Das P, Golde TE. Chakrabarty P, et al. Nat Neurosci. 2011 Jun;14(6):694-6. doi: 10.1038/nn.2829. Epub 2011 May 15. Nat Neurosci. 2011. PMID: 21572432 Free PMC article.

6

Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.

Moore BD, Chakrabarty P, Levites Y, Kukar TL, Baine AM, Moroni T, Ladd TB, Das P, Dickson DW, Golde TE. Moore BD, et al. Among authors: chakrabarty p. Alzheimers Res Ther. 2012 May 23;4(3):18. doi: 10.1186/alzrt121. Alzheimers Res Ther. 2012. PMID: 22621179 Free PMC article.

7

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition.

Chakrabarty P, Tianbai L, Herring A, Ceballos-Diaz C, Das P, Golde TE. Chakrabarty P, et al. Mol Neurodegener. 2012 Jul 29;7:36. doi: 10.1186/1750-1326-7-36. Mol Neurodegener. 2012. PMID: 22838967 Free PMC article.

8

Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology.

Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Das P, et al. Among authors: chakrabarty p. Mol Neurodegener. 2012 Aug 14;7:39. doi: 10.1186/1750-1326-7-39. Mol Neurodegener. 2012. PMID: 22892055 Free PMC article.

9

Normal cognition in transgenic BRI2-Aβ mice.

Kim J, Chakrabarty P, Hanna A, March A, Dickson DW, Borchelt DR, Golde T, Janus C. Kim J, et al. Among authors: chakrabarty p. Mol Neurodegener. 2013 May 12;8:15. doi: 10.1186/1750-1326-8-15. Mol Neurodegener. 2013. PMID: 23663320 Free PMC article.

10

Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.

Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, Petrucelli L, Sahara N, Dickson DW, Giasson B, Lewis J. Clippinger AK, et al. Among authors: chakrabarty p. Acta Neuropathol. 2013 Jul;126(1):39-50. doi: 10.1007/s00401-013-1123-8. Epub 2013 May 11. Acta Neuropathol. 2013. PMID: 23666556 Free PMC article.

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