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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
2000 1
2002 1
2003 1
2004 1
2005 1
2007 1
2008 3
2009 3
2011 4
2012 11
2013 16
2014 16
2015 23
2016 37
2017 33
2018 44
2019 53
2020 67
2021 91
2022 45
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411 results
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Challenges in the analysis of long noncoding RNA functionality.
Leone S, Santoro R. Leone S, et al. FEBS Lett. 2016 Aug;590(15):2342-53. doi: 10.1002/1873-3468.12308. Epub 2016 Jul 26. FEBS Lett. 2016. PMID: 27417130 Free article. Review.
Long noncoding RNA (lncRNA) are emerging as important regulators of diverse biological functions. ...In this review, we discuss the strengths and weaknesses of available techniques for the analysis of chromatin-associated lncRNA and emerging mod
Long noncoding RNA (lncRNA) are emerging as important regulators of diverse biological functions. ...In this rev
RNA Sequencing and Analysis.
Kukurba KR, Montgomery SB. Kukurba KR, et al. Cold Spring Harb Protoc. 2015 Apr 13;2015(11):951-69. doi: 10.1101/pdb.top084970. Cold Spring Harb Protoc. 2015. PMID: 25870306 Free PMC article.
Recent advances in the RNA-Seq workflow, from sample preparation to library construction to data analysis, have enabled researchers to further elucidate the functional complexity of the transcription. In addition to polyadenylated messenger RNA (mRNA) …
Recent advances in the RNA-Seq workflow, from sample preparation to library construction to data analysis, have enabled resear …
Technological Developments in lncRNA Biology.
Jathar S, Kumar V, Srivastava J, Tripathi V. Jathar S, et al. Adv Exp Med Biol. 2017;1008:283-323. doi: 10.1007/978-981-10-5203-3_10. Adv Exp Med Biol. 2017. PMID: 28815544 Review.
One of the rapidly expanding fields of this class of transcripts is the regulatory lncRNAs, which had been a major challenge in terms of their molecular functions and mechanisms of action. ...Here, we review the current methodologies available for discovering and in …
One of the rapidly expanding fields of this class of transcripts is the regulatory lncRNAs, which had been a major challenge in terms …
Long Noncoding RNA EBLN3P Promotes the Progression of Liver Cancer via Alteration of microRNA-144-3p/DOCK4 Signal.
Li H, Wang M, Zhou H, Lu S, Zhang B. Li H, et al. Cancer Manag Res. 2020 Sep 29;12:9339-9349. doi: 10.2147/CMAR.S261976. eCollection 2020. Cancer Manag Res. 2020. PMID: 33061623 Free PMC article.
BACKGROUND: Therapy for patients with liver cancer in the advanced stage remains a great challenge, and there are very few approved treatments. Although accumulated evidence demonstrates the importance of lncRNAs in liver cancer, data on the functional roles and mol …
BACKGROUND: Therapy for patients with liver cancer in the advanced stage remains a great challenge, and there are very few approved t …
Systematic review of blood diagnostic markers in colorectal cancer.
Nikolaou S, Qiu S, Fiorentino F, Rasheed S, Tekkis P, Kontovounisios C. Nikolaou S, et al. Tech Coloproctol. 2018 Jul;22(7):481-498. doi: 10.1007/s10151-018-1820-3. Epub 2018 Jul 18. Tech Coloproctol. 2018. PMID: 30022330 Free PMC article. Review.
The markers were divided in broadly four groups: nucleic acids (RNA/DNA/messenger RNA/microRNAs), cytokines, antibodies, and proteins. The most promising circulating markers identified among the nucleid acids were NEAT_v2 non-coding RNA, SDC2 methylated DNA, …
The markers were divided in broadly four groups: nucleic acids (RNA/DNA/messenger RNA/microRNAs), cytokines, antibodies, and p …
Identification of a Ferroptosis-Related LncRNA Signature as a Novel Prognosis Model for Lung Adenocarcinoma.
Lu L, Liu LP, Zhao QQ, Gui R, Zhao QY. Lu L, et al. Front Oncol. 2021 Jun 23;11:675545. doi: 10.3389/fonc.2021.675545. eCollection 2021. Front Oncol. 2021. PMID: 34249715 Free PMC article.
It is essential to determine the prognostic value of ferroptosis-related lncRNAs in LUAD. In this study, we obtained RNA sequencing (RNA-seq) data and corresponding clinical information of LUAD patients from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus …
It is essential to determine the prognostic value of ferroptosis-related lncRNAs in LUAD. In this study, we obtained RNA sequencing ( …
DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma.
Lu C, Wei Y, Wang X, Zhang Z, Yin J, Li W, Chen L, Lyu X, Shi Z, Yan W, You Y. Lu C, et al. Mol Cancer. 2020 Feb 10;19(1):28. doi: 10.1186/s12943-020-1137-5. Mol Cancer. 2020. PMID: 32039732 Free PMC article.
BACKGROUND: Accumulating evidence shows that long noncoding RNAs (lncRNAs) are important regulator molecules involved in diverse biological processes. ...Disinhibition of MAPK1 regulated TMZ-induced cell apoptosis and the G1/S cell cycle transition by activat …
BACKGROUND: Accumulating evidence shows that long noncoding RNAs (lncRNAs) are important regulator molecules involved in diver …
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J. Zhou C, et al. Mol Cancer. 2020 Jul 29;19(1):118. doi: 10.1186/s12943-020-01237-y. Mol Cancer. 2020. PMID: 32727463 Free PMC article.
The development of resistance to gemcitabine is still a major challenge. The long noncoding RNA PVT1 was reported to be involved in carcinogenesis and chemoresistance; however, the mechanism by which PVT1 regulates the sensitivity of pancreatic cancer …
The development of resistance to gemcitabine is still a major challenge. The long noncoding RNA PVT1 was reporte …
CancerSEA: a cancer single-cell state atlas.
Yuan H, Yan M, Zhang G, Liu W, Deng C, Liao G, Xu L, Luo T, Yan H, Long Z, Shi A, Zhao T, Xiao Y, Li X. Yuan H, et al. Nucleic Acids Res. 2019 Jan 8;47(D1):D900-D908. doi: 10.1093/nar/gky939. Nucleic Acids Res. 2019. PMID: 30329142 Free PMC article.
High functional heterogeneity of cancer cells poses a major challenge for cancer research. ...It allows querying which functional states are associated with the gene (or gene list) of interest in different cancers. ...
High functional heterogeneity of cancer cells poses a major challenge for cancer research. ...It allows querying which func
Identification of Ferroptosis-Related Long Noncoding RNA and Construction of a Novel Prognostic Signature for Gastric Cancer.
Chen W, Feng Z, Huang J, Fu P, Xiong J, Cao Y, Liu Y, Tu Y, Li Z, Jie Z, Xiao T. Chen W, et al. Dis Markers. 2021 Aug 3;2021:7724997. doi: 10.1155/2021/7724997. eCollection 2021. Dis Markers. 2021. PMID: 34394774 Free PMC article.
The roles and prognostic value of ferroptosis-related long noncoding RNAs (lncRNAs) in gastric cancer remain unknown. RESULTS: In the current study, 20 ferroptosis-related lncRNAs were identified via univariate Cox analysis, least absolute shrinkage, and sele …
The roles and prognostic value of ferroptosis-related long noncoding RNAs (lncRNAs) in gastric cancer remain unknown. RESULTS: …
411 results