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The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes.
Chamberlain LH, Gould GW. Chamberlain LH, et al. J Biol Chem. 2002 Dec 20;277(51):49750-4. doi: 10.1074/jbc.M206936200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376543
Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.
Perera HK, Clarke M, Morris NJ, Hong W, Chamberlain LH, Gould GW. Perera HK, et al. Mol Biol Cell. 2003 Jul;14(7):2946-58. doi: 10.1091/mbc.e02-11-0722. Epub 2003 Apr 4. Mol Biol Cell. 2003. PMID: 12857877 Free PMC article.
Neomycin prevents the wortmannin inhibition of insulin-stimulated Glut4 translocation and glucose transport in 3T3-L1 adipocytes.
James DJ, Salaün C, Brandie FM, Connell JM, Chamberlain LH. James DJ, et al. J Biol Chem. 2004 May 14;279(20):20567-70. doi: 10.1074/jbc.C400096200. Epub 2004 Mar 15. J Biol Chem. 2004. PMID: 15024008
Lipid rafts and the regulation of exocytosis.
Salaün C, James DJ, Chamberlain LH. Salaün C, et al. Traffic. 2004 Apr;5(4):255-64. doi: 10.1111/j.1600-0854.2004.0162.x. Traffic. 2004. PMID: 15030567 Free PMC article. Review.
Plasma membrane targeting of exocytic SNARE proteins.
Salaün C, James DJ, Greaves J, Chamberlain LH. Salaün C, et al. Biochim Biophys Acta. 2004 Aug 23;1693(2):81-9. doi: 10.1016/j.bbamcr.2004.05.008. Biochim Biophys Acta. 2004. PMID: 15313010 Review.
The SNARE proteins SNAP-25 and SNAP-23 display different affinities for lipid rafts in PC12 cells. Regulation by distinct cysteine-rich domains.
Salaün C, Gould GW, Chamberlain LH. Salaün C, et al. J Biol Chem. 2005 Jan 14;280(2):1236-40. doi: 10.1074/jbc.M410674200. Epub 2004 Nov 12. J Biol Chem. 2005. PMID: 15542596 Free PMC article.
Lipid raft association of SNARE proteins regulates exocytosis in PC12 cells.
Salaün C, Gould GW, Chamberlain LH. Salaün C, et al. J Biol Chem. 2005 May 20;280(20):19449-53. doi: 10.1074/jbc.M501923200. Epub 2005 Mar 15. J Biol Chem. 2005. PMID: 15769746 Free PMC article.
Dual role of the cysteine-string domain in membrane binding and palmitoylation-dependent sorting of the molecular chaperone cysteine-string protein.
Greaves J, Chamberlain LH. Greaves J, et al. Mol Biol Cell. 2006 Nov;17(11):4748-59. doi: 10.1091/mbc.e06-03-0183. Epub 2006 Aug 30. Mol Biol Cell. 2006. PMID: 16943324 Free PMC article.
Palmitoylation-dependent protein sorting.
Greaves J, Chamberlain LH. Greaves J, et al. J Cell Biol. 2007 Jan 29;176(3):249-54. doi: 10.1083/jcb.200610151. Epub 2007 Jan 22. J Cell Biol. 2007. PMID: 17242068 Free PMC article. Review.
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