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Physiological functions of mitochondrial fusion.
Chen H, Chan DC. Chen H, et al. Among authors: chan dc. Ann N Y Acad Sci. 2010 Jul;1201:21-5. doi: 10.1111/j.1749-6632.2010.05615.x. Ann N Y Acad Sci. 2010. PMID: 20649534 Review.
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC. Chen H, et al. Among authors: chan dc. J Cell Biol. 2003 Jan 20;160(2):189-200. doi: 10.1083/jcb.200211046. Epub 2003 Jan 13. J Cell Biol. 2003. PMID: 12527753 Free PMC article.
Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis.
Karbowski M, Arnoult D, Chen H, Chan DC, Smith CL, Youle RJ. Karbowski M, et al. Among authors: chan dc. J Cell Biol. 2004 Feb 16;164(4):493-9. doi: 10.1083/jcb.200309082. Epub 2004 Feb 9. J Cell Biol. 2004. PMID: 14769861 Free PMC article.
Mitochondrial dynamics in mammals.
Chen H, Chan DC. Chen H, et al. Among authors: chan dc. Curr Top Dev Biol. 2004;59:119-44. doi: 10.1016/S0070-2153(04)59005-1. Curr Top Dev Biol. 2004. PMID: 14975249 Review. No abstract available.
Structural basis of mitochondrial tethering by mitofusin complexes.
Koshiba T, Detmer SA, Kaiser JT, Chen H, McCaffery JM, Chan DC. Koshiba T, et al. Among authors: chan dc. Science. 2004 Aug 6;305(5685):858-62. doi: 10.1126/science.1099793. Science. 2004. PMID: 15297672
Fueling synapses.
Schuman E, Chan D. Schuman E, et al. Among authors: chan d. Cell. 2004 Dec 17;119(6):738-40. doi: 10.1016/j.cell.2004.12.003. Cell. 2004. PMID: 15607970
The fusion activity of HIV-1 gp41 depends on interhelical interactions.
Suntoke TR, Chan DC. Suntoke TR, et al. Among authors: chan dc. J Biol Chem. 2005 May 20;280(20):19852-7. doi: 10.1074/jbc.M502196200. Epub 2005 Mar 16. J Biol Chem. 2005. PMID: 15772068
Disruption of fusion results in mitochondrial heterogeneity and dysfunction.
Chen H, Chomyn A, Chan DC. Chen H, et al. Among authors: chan dc. J Biol Chem. 2005 Jul 15;280(28):26185-92. doi: 10.1074/jbc.M503062200. Epub 2005 May 17. J Biol Chem. 2005. PMID: 15899901
The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria.
Griffin EE, Graumann J, Chan DC. Griffin EE, et al. Among authors: chan dc. J Cell Biol. 2005 Jul 18;170(2):237-48. doi: 10.1083/jcb.200503148. Epub 2005 Jul 11. J Cell Biol. 2005. PMID: 16009724 Free PMC article.
Emerging functions of mammalian mitochondrial fusion and fission.
Chen H, Chan DC. Chen H, et al. Among authors: chan dc. Hum Mol Genet. 2005 Oct 15;14 Spec No. 2:R283-9. doi: 10.1093/hmg/ddi270. Hum Mol Genet. 2005. PMID: 16244327 Review.
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