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Liver X Receptors as Therapeutic Targets for Managing Cholesterol: Implications for Atherosclerosis and Other Inflammatory Conditions.
Zhang Y, Chan JF, Cummins CL. Zhang Y, et al. Among authors: chan jf. Clin Lipidol. 2009 Feb;4(1):29-40. doi: 10.2217/17584299.4.1.29. Clin Lipidol. 2009. PMID: 20852746 Free PMC article.
LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.
Patel R, Patel M, Tsai R, Lin V, Bookout AL, Zhang Y, Magomedova L, Li T, Chan JF, Budd C, Mangelsdorf DJ, Cummins CL. Patel R, et al. Among authors: chan jf. J Clin Invest. 2011 Jan;121(1):431-41. doi: 10.1172/JCI41681. Epub 2010 Dec 1. J Clin Invest. 2011. PMID: 21123945 Free PMC article.
Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein.
Wang X, Lam JY, Wong WM, Yuen CK, Cai JP, Au SW, Chan JF, To KKW, Kok KH, Yuen KY. Wang X, et al. Among authors: chan jf. mBio. 2020 Oct 20;11(5):e02431-20. doi: 10.1128/mBio.02431-20. mBio. 2020. PMID: 33082264
Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters.
Yuan S, Wang R, Chan JF, Zhang AJ, Cheng T, Chik KK, Ye ZW, Wang S, Lee AC, Jin L, Li H, Jin DY, Yuen KY, Sun H. Yuan S, et al. Among authors: chan jf. Nat Microbiol. 2020 Oct 7. doi: 10.1038/s41564-020-00802-x. Online ahead of print. Nat Microbiol. 2020. PMID: 33028965
Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters.
Lee AC, Zhang AJ, Chan JF, Li C, Fan Z, Liu F, Chen Y, Liang R, Sridhar S, Cai JP, Poon VK, Chan CC, To KK, Yuan S, Zhou J, Chu H, Yuen KY. Lee AC, et al. Among authors: chan jf. Cell Rep Med. 2020 Oct 20;1(7):100121. doi: 10.1016/j.xcrm.2020.100121. Epub 2020 Sep 22. Cell Rep Med. 2020. PMID: 32984855 Free PMC article.
The Coronavirus Disease 2019 pandemic: how does it spread and how do we stop it?
Li X, Sridhar S, Chan JF. Li X, et al. Among authors: chan jf. Curr Opin HIV AIDS. 2020 Nov;15(6):328-335. doi: 10.1097/COH.0000000000000650. Curr Opin HIV AIDS. 2020. PMID: 32969975 Review.
Animal models for COVID-19.
Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, Segalés J, Vasan SS, Henao-Restrepo AM, Barouch DH. Muñoz-Fontela C, et al. Among authors: chan jfw. Nature. 2020 Sep 23. doi: 10.1038/s41586-020-2787-6. Online ahead of print. Nature. 2020. PMID: 32967005 Review.
Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms.
Li X, Chan JF, Li KK, Tso EY, Yip CC, Sridhar S, Chung TW, Chiu KH, Hung DL, Wu AK, Chau SK, Liu R, Lung KC, Tam AR, Cheng VC, To KK, Chan KH, Hung IF, Yuen KY. Li X, et al. Among authors: chan jf. Infection. 2020 Sep 17:1-9. doi: 10.1007/s15010-020-01524-2. Online ahead of print. Infection. 2020. PMID: 32944840 Free PMC article.
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target.
Yuan S, Chu H, Huang J, Zhao X, Ye ZW, Lai PM, Wen L, Cai JP, Mo Y, Cao J, Liang R, Poon VK, Sze KH, Zhou J, To KK, Chen Z, Chen H, Jin DY, Chan JF, Yuen KY. Yuan S, et al. Among authors: chan jf. Sci Adv. 2020 Aug 28;6(35):eaba7910. doi: 10.1126/sciadv.aba7910. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32923629 Free PMC article.
Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay.
Fong CH, Cai JP, Dissanayake TK, Chen LL, Choi CY, Wong LH, Ng AC, Pang PKP, Ho DT, Poon RW, Chung TW, Sridhar S, Chan KH, Chan JF, Hung IF, Yuen KY, To KK. Fong CH, et al. Among authors: chan jf. Int J Mol Sci. 2020 Sep 9;21(18):6595. doi: 10.3390/ijms21186595. Int J Mol Sci. 2020. PMID: 32916926 Free PMC article.
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