Chan JN - Search Results

1

Recent advances and method development for drug target identification.

Chan JN, Nislow C, Emili A. Chan JN, et al. Trends Pharmacol Sci. 2010 Feb;31(2):82-8. doi: 10.1016/j.tips.2009.11.002. Epub 2009 Dec 7. Trends Pharmacol Sci. 2010. PMID: 20004028 Review.

2

Perinuclear cohibin complexes maintain replicative life span via roles at distinct silent chromatin domains.

Chan JN, Poon BP, Salvi J, Olsen JB, Emili A, Mekhail K. Chan JN, et al. Dev Cell. 2011 Jun 14;20(6):867-79. doi: 10.1016/j.devcel.2011.05.014. Dev Cell. 2011. PMID: 21664583 Free article.

3

Target identification by chromatographic co-elution: monitoring of drug-protein interactions without immobilization or chemical derivatization.

Chan JN, Vuckovic D, Sleno L, Olsen JB, Pogoutse O, Havugimana P, Hewel JA, Bajaj N, Wang Y, Musteata MF, Nislow C, Emili A. Chan JN, et al. Mol Cell Proteomics. 2012 Jul;11(7):M111.016642. doi: 10.1074/mcp.M111.016642. Epub 2012 Feb 22. Mol Cell Proteomics. 2012. PMID: 22357554 Free PMC article.

4

Roles for Pbp1 and caloric restriction in genome and lifespan maintenance via suppression of RNA-DNA hybrids.

Salvi JS, Chan JN, Szafranski K, Liu TT, Wu JD, Olsen JB, Khanam N, Poon BP, Emili A, Mekhail K. Salvi JS, et al. Among authors: chan jn. Dev Cell. 2014 Jul 28;30(2):177-91. doi: 10.1016/j.devcel.2014.05.013. Dev Cell. 2014. PMID: 25073155 Free article.

5

Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1.

Salvi JS, Chan JN, Pettigrew C, Liu TT, Wu JD, Mekhail K. Salvi JS, et al. Among authors: chan jn. Aging Cell. 2013 Feb;12(1):67-75. doi: 10.1111/acel.12020. Epub 2012 Nov 23. Aging Cell. 2013. PMID: 23082874 Free article.

6

Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process.

Chung DK, Chan JN, Strecker J, Zhang W, Ebrahimi-Ardebili S, Lu T, Abraham KJ, Durocher D, Mekhail K. Chung DK, et al. Among authors: chan jn. Nat Commun. 2015 Jul 24;6:7742. doi: 10.1038/ncomms8742. Nat Commun. 2015. PMID: 26205667 Free article.

7

Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids.

Abraham KJ, Chan JN, Salvi JS, Ho B, Hall A, Vidya E, Guo R, Killackey SA, Liu N, Lee JE, Brown GW, Mekhail K. Abraham KJ, et al. Among authors: chan jn. Nucleic Acids Res. 2016 Oct 14;44(18):8870-8884. doi: 10.1093/nar/gkw752. Epub 2016 Aug 29. Nucleic Acids Res. 2016. PMID: 27574117 Free PMC article.

8

Nucleolar RNA polymerase II drives ribosome biogenesis.

Abraham KJ, Khosraviani N, Chan JNY, Gorthi A, Samman A, Zhao DY, Wang M, Bokros M, Vidya E, Ostrowski LA, Oshidari R, Pietrobon V, Patel PS, Algouneh A, Singhania R, Liu Y, Yerlici VT, De Carvalho DD, Ohh M, Dickson BC, Hakem R, Greenblatt JF, Lee S, Bishop AJR, Mekhail K. Abraham KJ, et al. Nature. 2020 Sep;585(7824):298-302. doi: 10.1038/s41586-020-2497-0. Epub 2020 Jul 15. Nature. 2020. PMID: 32669707 Free PMC article.

9

Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair.

Oshidari R, Strecker J, Chung DKC, Abraham KJ, Chan JNY, Damaren CJ, Mekhail K. Oshidari R, et al. Nat Commun. 2018 Jul 2;9(1):2567. doi: 10.1038/s41467-018-05009-7. Nat Commun. 2018. PMID: 29967403 Free PMC article.

10

DNA double-strand break-capturing nuclear envelope tubules drive DNA repair.

Shokrollahi M, Stanic M, Hundal A, Chan JNY, Urman D, Jordan CA, Hakem A, Espin R, Hao J, Krishnan R, Maass PG, Dickson BC, Hande MP, Pujana MA, Hakem R, Mekhail K. Shokrollahi M, et al. Among authors: chan jny. Nat Struct Mol Biol. 2024 Apr 17. doi: 10.1038/s41594-024-01286-7. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38632359

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

49 results

Search Page