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4,036 results
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A fine balance: an autoregulatory gene therapy approach to treat obesity and achieve energy homeostasis.
Samson SL, Kohjima M, Chan L. Samson SL, et al. Among authors: chan l. Gene Ther. 2009 Oct;16(10):1175-7. doi: 10.1038/gt.2009.88. Epub 2009 Jul 23. Gene Ther. 2009. PMID: 19626055 Free PMC article. No abstract available.
Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice.
Li R, Buras E, Lee J, Liu R, Liu V, Espiritu C, Ozer K, Thompson B, Nally L, Yuan G, Oka K, Chang B, Samson S, Yechoor V, Chan L. Li R, et al. Among authors: chan l. Gene Ther. 2015 Nov;22(11):876-82. doi: 10.1038/gt.2015.62. Epub 2015 Jul 14. Gene Ther. 2015. PMID: 26172077 Free PMC article.
Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma.
Sundarasetty BS, Chan L, Darling D, Giunti G, Farzaneh F, Schenck F, Naundorf S, Kuehlcke K, Ruggiero E, Schmidt M, von Kalle C, Rothe M, Hoon DS, Gerasch L, Figueiredo C, Koehl U, Blasczyk R, Gutzmer R, Stripecke R. Sundarasetty BS, et al. Among authors: chan l. Gene Ther. 2015 Sep;22(9):707-20. doi: 10.1038/gt.2015.43. Epub 2015 May 28. Gene Ther. 2015. PMID: 25965393 Free PMC article.
Gene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector.
Oka K, Mullins CE, Kushwaha RS, Leen AM, Chan L. Oka K, et al. Among authors: chan l. Gene Ther. 2015 Jan;22(1):87-95. doi: 10.1038/gt.2014.85. Epub 2014 Sep 18. Gene Ther. 2015. PMID: 25231173 Free PMC article.
Rescue administration of a helper-dependent adenovirus vector with long-term efficacy in dogs with glycogen storage disease type Ia.
Crane B, Luo X, Demaster A, Williams KD, Kozink DM, Zhang P, Brown TT, Pinto CR, Oka K, Sun F, Jackson MW, Chan L, Koeberl DD. Crane B, et al. Among authors: chan l. Gene Ther. 2012 Apr;19(4):443-52. doi: 10.1038/gt.2011.86. Epub 2011 Jun 9. Gene Ther. 2012. PMID: 21654821
Efficacy of helper-dependent adenovirus vector-mediated gene therapy in murine glycogen storage disease type Ia.
Koeberl DD, Sun B, Bird A, Chen YT, Oka K, Chan L. Koeberl DD, et al. Among authors: chan l. Mol Ther. 2007 Jul;15(7):1253-8. doi: 10.1038/sj.mt.6300188. Epub 2007 May 15. Mol Ther. 2007. PMID: 17505475
Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector.
Oka K, Belalcazar LM, Dieker C, Nour EA, Nuno-Gonzalez P, Paul A, Cormier S, Shin JK, Finegold M, Chan L. Oka K, et al. Among authors: chan l. Gene Ther. 2007 Feb;14(3):191-202. doi: 10.1038/sj.gt.3302819. Epub 2006 Sep 7. Gene Ther. 2007. PMID: 16957769 Free PMC article.
Gene therapy progress and prospects: gene therapy for diabetes mellitus.
Yechoor V, Chan L. Yechoor V, et al. Among authors: chan l. Gene Ther. 2005 Jan;12(2):101-7. doi: 10.1038/sj.gt.3302412. Gene Ther. 2005. PMID: 15496957 Review.
Enhanced in vitro and in vivo gene delivery using cationic agent complexed retrovirus vectors.
Themis M, Forbes SJ, Chan L, Cooper RG, Etheridge CJ, Miller AD, Hodgson HJ, Coutelle C. Themis M, et al. Among authors: chan l. Gene Ther. 1998 Sep;5(9):1180-6. doi: 10.1038/sj.gt.3300715. Gene Ther. 1998. PMID: 9930318
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia.
Nomura S, Merched A, Nour E, Dieker C, Oka K, Chan L. Nomura S, et al. Among authors: chan l. Gene Ther. 2004 Oct;11(20):1540-8. doi: 10.1038/sj.gt.3302310. Gene Ther. 2004. PMID: 15269711
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