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Vaccination With Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model.
Fernandez J, Sanders H, Henn J, Wilson JM, Malone D, Buoninfante A, Willms M, Chan R, DuMont AL, McLahan C, Grubb K, Romanello A, van den Dobbelsteen G, Torres VJ, Poolman JT. Fernandez J, et al. Among authors: chan r. J Infect Dis. 2022 Apr 19;225(8):1460-1470. doi: 10.1093/infdis/jiab219. J Infect Dis. 2022. PMID: 33895843 Free PMC article.
Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice.
Lubkin A, Lee WL, Alonzo F 3rd, Wang C, Aligo J, Keller M, Girgis NM, Reyes-Robles T, Chan R, O'Malley A, Buckley P, Vozhilla N, Vasquez MT, Su J, Sugiyama M, Yeung ST, Coffre M, Bajwa S, Chen E, Martin P, Kim SY, Loomis C, Worthen GS, Shopsin B, Khanna KM, Weinstock D, Lynch AS, Koralov SB, Loke P, Cadwell K, Torres VJ. Lubkin A, et al. Among authors: chan r. Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9. doi: 10.1016/j.chom.2019.01.015. Epub 2019 Feb 21. Cell Host Microbe. 2019. PMID: 30799265 Free PMC article.
The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus.
Sause WE, Balasubramanian D, Irnov I, Copin R, Sullivan MJ, Sommerfield A, Chan R, Dhabaria A, Askenazi M, Ueberheide B, Shopsin B, van Bakel H, Torres VJ. Sause WE, et al. Among authors: chan r. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13563-13572. doi: 10.1073/pnas.1904280116. Epub 2019 Jun 19. Proc Natl Acad Sci U S A. 2019. PMID: 31217288 Free PMC article.
Genetic variation of staphylococcal LukAB toxin determines receptor tropism.
Perelman SS, James DBA, Boguslawski KM, Nelson CW, Ilmain JK, Zwack EE, Prescott RA, Mohamed A, Tam K, Chan R, Narechania A, Pawline MB, Vozhilla N, Moustafa AM, Kim SY, Dittmann M, Ekiert DC, Bhabha G, Shopsin B, Planet PJ, Koralov SB, Torres VJ. Perelman SS, et al. Among authors: chan r. Nat Microbiol. 2021 Jun;6(6):731-745. doi: 10.1038/s41564-021-00890-3. Epub 2021 Apr 19. Nat Microbiol. 2021. PMID: 33875847 Free PMC article.
Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Buckley PT, Chan R, Fernandez J, Luo J, Lacey KA, DuMont AL, O'Malley A, Brezski RJ, Zheng S, Malia T, Whitaker B, Zwolak A, Payne A, Clark D, Sigg M, Lacy ER, Kornilova A, Kwok D, McCarthy S, Wu B, Morrow B, Nemeth-Seay J, Petley T, Wu S, Strohl WR, Lynch AS, Torres VJ. Buckley PT, et al. Among authors: chan r. Cell Host Microbe. 2023 May 10;31(5):751-765.e11. doi: 10.1016/j.chom.2023.04.004. Epub 2023 Apr 24. Cell Host Microbe. 2023. PMID: 37098341 Free article.
3,711 results