Chan SL - Search Results

1

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. Stein TD, et al. Among authors: chan sl. J Neurosci. 2004 Sep 1;24(35):7707-17. doi: 10.1523/JNEUROSCI.2211-04.2004. J Neurosci. 2004. PMID: 15342738 Free PMC article.

2

Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity.

Lee J, Kim SJ, Son TG, Chan SL, Mattson MP. Lee J, et al. Among authors: chan sl. J Neurosci Res. 2006 Jun;83(8):1552-7. doi: 10.1002/jnr.20831. J Neurosci Res. 2006. PMID: 16521127

3

Electrophysiological and cerebrovascular effects of the alpha-secretase-derived form of amyloid precursor protein in young and middle-aged rats.

Sánchez-Alavez M, Chan SL, Mattson MP, Criado JR. Sánchez-Alavez M, et al. Among authors: chan sl. Brain Res. 2007 Feb 2;1131(1):112-7. doi: 10.1016/j.brainres.2006.10.074. Epub 2006 Dec 8. Brain Res. 2007. PMID: 17157827

4

Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.

Kyriazis GA, Wei Z, Vandermey M, Jo DG, Xin O, Mattson MP, Chan SL. Kyriazis GA, et al. Among authors: chan sl. J Biol Chem. 2008 Sep 12;283(37):25492-25502. doi: 10.1074/jbc.M802072200. Epub 2008 Jul 2. J Biol Chem. 2008. PMID: 18599481 Free PMC article.

5

Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease.

Chan SL, Pedersen WA, Zhu H, Mattson MP. Chan SL, et al. Neuromolecular Med. 2002;1(1):55-67. doi: 10.1385/NMM:1:1:55. Neuromolecular Med. 2002. PMID: 12025816

6

Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain.

Lee J, Chan SL, Mattson MP. Lee J, et al. Among authors: chan sl. Neuromolecular Med. 2002;2(1):29-45. doi: 10.1385/NMM:2:1:29. Neuromolecular Med. 2002. PMID: 12230303

7

Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease.

Chan SL, Furukawa K, Mattson MP. Chan SL, et al. Neuromolecular Med. 2002;2(2):167-96. doi: 10.1385/NMM:2:2:167. Neuromolecular Med. 2002. PMID: 12428810 Review.

8

Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice.

Pak K, Chan SL, Mattson MP. Pak K, et al. Among authors: chan sl. Neuromolecular Med. 2003;3(1):53-64. doi: 10.1385/NMM:3:1:53. Neuromolecular Med. 2003. PMID: 12665676

9

Homocysteine and folate deficiency sensitize oligodendrocytes to the cell death-promoting effects of a presenilin-1 mutation and amyloid beta-peptide.

Pak KJ, Chan SL, Mattson MP. Pak KJ, et al. Among authors: chan sl. Neuromolecular Med. 2003;3(2):119-28. doi: 10.1385/NMM:3:2:119. Neuromolecular Med. 2003. PMID: 12728194

10

Good and bad amyloid antibodies.

Mattson MP, Chan SL. Mattson MP, et al. Among authors: chan sl. Science. 2003 Sep 26;301(5641):1847-9. doi: 10.1126/science.301.5641.1847. Science. 2003. PMID: 14512605 No abstract available.

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