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Nitazoxanide, tizoxanide and a new analogue [4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide; NTB] inhibit the growth of kinetoplastid parasites (Trypanosoma cruzi and Leishmania mexicana) in vitro.
Chan-Bacab MJ, Hernández-Núñez E, Navarrete-Vázquez G. Chan-Bacab MJ, et al. J Antimicrob Chemother. 2009 Jun;63(6):1292-3. doi: 10.1093/jac/dkp117. Epub 2009 Apr 4. J Antimicrob Chemother. 2009. PMID: 19346519 No abstract available.
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity.
Navarrete-Vazquez G, Chávez-Silva F, Argotte-Ramos R, Rodríguez-Gutiérrez Mdel C, Chan-Bacab MJ, Cedillo-Rivera R, Moo-Puc R, Hernández-Nuñez E. Navarrete-Vazquez G, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):3168-71. doi: 10.1016/j.bmcl.2011.02.100. Epub 2011 Feb 26. Bioorg Med Chem Lett. 2011. PMID: 21397502
Synthesis, Screening and in silico Simulations of Anti-Parasitic Propamidine/Benzimidazole Derivatives.
Mendez-Cuesta CA, Herrera-Rueda MA, Hidalgo-Figueroa S, Tlahuext H, Moo-Puc R, Chale-Dzul JB, Chan-Bacab M, Ortega-Morales BO, Hernandez-Nunez E, Mendez-Lucio O, Medina-Franco JL, Navarrete-Vazquez G. Mendez-Cuesta CA, et al. Med Chem. 2017;13(2):137-148. doi: 10.2174/1573406412666160811112408. Med Chem. 2017. PMID: 27527618
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum.
Colín-Lozano B, León-Rivera I, Chan-Bacab MJ, Ortega-Morales BO, Moo-Puc R, López-Guerrero V, Hernández-Núñez E, Argüello-Garcia R, Scior T, Barbosa-Cabrera E, Navarrete-Vázquez G. Colín-Lozano B, et al. Among authors: chan bacab mj. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3490-3494. doi: 10.1016/j.bmcl.2017.05.071. Epub 2017 May 24. Bioorg Med Chem Lett. 2017. PMID: 28645659
Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.
Nava-Zuazo C, Estrada-Soto S, Guerrero-Alvarez J, León-Rivera I, Molina-Salinas GM, Said-Fernández S, Chan-Bacab MJ, Cedillo-Rivera R, Moo-Puc R, Mirón-López G, Navarrete-Vazquez G. Nava-Zuazo C, et al. Bioorg Med Chem. 2010 Sep 1;18(17):6398-403. doi: 10.1016/j.bmc.2010.07.008. Epub 2010 Jul 30. Bioorg Med Chem. 2010. PMID: 20674375
Design, synthesis and in vitro antiprotozoal activity of benzimidazole-pentamidine hybrids.
Torres-Gómez H, Hernández-Núñez E, León-Rivera I, Guerrero-Alvarez J, Cedillo-Rivera R, Moo-Puc R, Argotte-Ramos R, Rodríguez-Gutiérrez Mdel C, Chan-Bacab MJ, Navarrete-Vázquez G. Torres-Gómez H, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3147-51. doi: 10.1016/j.bmcl.2008.05.009. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18486471
Antiprotozoal and cytotoxic studies on some isocordoin derivatives.
Borges-Argáez R, Vela-Catzín T, Yam-Puc A, Chan-Bacab MJ, Moo-Puc RE, Cáceres-Farfán M. Borges-Argáez R, et al. Planta Med. 2009 Oct;75(12):1336-8. doi: 10.1055/s-0029-1185670. Epub 2009 May 8. Planta Med. 2009. PMID: 19431103
In vitro activity of Tridax procumbens against promastigotes of Leishmania mexicana.
Martín-Quintal Z, Moo-Puc R, González-Salazar F, Chan-Bacab MJ, Torres-Tapia LW, Peraza-Sánchez SR. Martín-Quintal Z, et al. J Ethnopharmacol. 2009 Apr 21;122(3):463-7. doi: 10.1016/j.jep.2009.01.037. Epub 2009 Feb 10. J Ethnopharmacol. 2009. PMID: 19429313
2-acylamino-5-nitro-1,3-thiazoles: preparation and in vitro bioevaluation against four neglected protozoan parasites.
Nava-Zuazo C, Chávez-Silva F, Moo-Puc R, Chan-Bacab MJ, Ortega-Morales BO, Moreno-Díaz H, Díaz-Coutiño D, Hernández-Núñez E, Navarrete-Vázquez G. Nava-Zuazo C, et al. Among authors: chan bacab mj. Bioorg Med Chem. 2014 Mar 1;22(5):1626-33. doi: 10.1016/j.bmc.2014.01.029. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24529307
Plant natural products with leishmanicidal activity.
Chan-Bacab MJ, Peña-Rodríguez LM. Chan-Bacab MJ, et al. Nat Prod Rep. 2001 Dec;18(6):674-88. doi: 10.1039/b100455g. Nat Prod Rep. 2001. PMID: 11820764 Review. No abstract available.
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