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Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
Muller AJ, Sharma MD, Chandler PR, Duhadaway JB, Everhart ME, Johnson BA 3rd, Kahler DJ, Pihkala J, Soler AP, Munn DH, Prendergast GC, Mellor AL. Muller AJ, et al. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17073-8. doi: 10.1073/pnas.0806173105. Epub 2008 Oct 24. Proc Natl Acad Sci U S A. 2008. PMID: 18952840 Free PMC article.
Physiologic control of IDO competence in splenic dendritic cells.
Baban B, Chandler PR, Johnson BA 3rd, Huang L, Li M, Sharpe ML, Francisco LM, Sharpe AH, Blazar BR, Munn DH, Mellor AL. Baban B, et al. J Immunol. 2011 Sep 1;187(5):2329-35. doi: 10.4049/jimmunol.1100276. Epub 2011 Aug 3. J Immunol. 2011. PMID: 21813777 Free PMC article.
473 results