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Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.
Parrish-Novak J, Xu W, Brender T, Yao L, Jones C, West J, Brandt C, Jelinek L, Madden K, McKernan PA, Foster DC, Jaspers S, Chandrasekher YA. Parrish-Novak J, et al. Among authors: chandrasekher ya. J Biol Chem. 2002 Dec 6;277(49):47517-23. doi: 10.1074/jbc.M205114200. Epub 2002 Sep 25. J Biol Chem. 2002. PMID: 12351624 Free article.
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist.
Xu W, Presnell SR, Parrish-Novak J, Kindsvogel W, Jaspers S, Chen Z, Dillon SR, Gao Z, Gilbert T, Madden K, Schlutsmeyer S, Yao L, Whitmore TE, Chandrasekher Y, Grant FJ, Maurer M, Jelinek L, Storey H, Brender T, Hammond A, Topouzis S, Clegg CH, Foster DC. Xu W, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9511-6. doi: 10.1073/pnas.171303198. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481447 Free PMC article.
Interleukin 20: discovery, receptor identification, and role in epidermal function.
Blumberg H, Conklin D, Xu WF, Grossmann A, Brender T, Carollo S, Eagan M, Foster D, Haldeman BA, Hammond A, Haugen H, Jelinek L, Kelly JD, Madden K, Maurer MF, Parrish-Novak J, Prunkard D, Sexson S, Sprecher C, Waggie K, West J, Whitmore TE, Yao L, Kuechle MK, Dale BA, Chandrasekher YA. Blumberg H, et al. Among authors: chandrasekher ya. Cell. 2001 Jan 12;104(1):9-19. doi: 10.1016/s0092-8674(01)00187-8. Cell. 2001. PMID: 11163236 Free article.
23 results