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CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat β-Thalassemia.
Frangoul H, Hanna R, Walters MC, Kao RL, Carroll C, McManus M, Chang KH, Jaskolka MC, Kim K, Yu Q, Badamosi N, Mei B, Afonja O, Thompson A; EdiThal Investigators. Frangoul H, et al. Among authors: chang kh. N Engl J Med. 2026 Apr 2;394(13):1292-1301. doi: 10.1056/NEJMoa2501277. N Engl J Med. 2026. PMID: 41931048 Clinical Trial.
CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat Sickle Cell Disease.
Hanna R, Frangoul H, Pineiro L, McKinney C, Mapara M, Dalal J, Rangarajan HG, Atkins H, Sharma A, Chang KH, Jaskolka MC, Kim K, Yu Q, Mei B, Afonja O, Walters MC; RUBY Investigators. Hanna R, et al. Among authors: chang kh. N Engl J Med. 2026 Apr 2;394(13):1281-1291. doi: 10.1056/NEJMoa2415550. N Engl J Med. 2026. PMID: 41931047 Clinical Trial.
Outcomes and disease activity during and after pregnancy in Asian women with MOGAD.
Hyun JW, Tian DC, Xu Y, Sakamoto N, Nishiyama S, Misu T, Ichikawa D, Nakashima I, Fujihara K, Pandit L, Vegda M, Yeo T, Tye JSN, Kang YR, Nam TS, Kim W, Chang KH, Viswanathan S, Hor JY, Tan HJ, Siritho S, Lee DE, Park NY, Kim SH, Kim HJ. Hyun JW, et al. Among authors: chang kh. Mult Scler. 2026 Feb 26:13524585261424657. doi: 10.1177/13524585261424657. Online ahead of print. Mult Scler. 2026. PMID: 41747756
1,177 results