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Novel Nanodimension artificial red blood cells that act as O2 and CO2 carrier with enhanced antioxidant activity: PLA-PEG nanoencapsulated PolySFHb-superoxide dismutase-catalase-carbonic anhydrase.
Gao W, Bian Y, Chang TM. Gao W, et al. Among authors: Chang TM. Artif Cells Nanomed Biotechnol. 2013 Aug;41(4):232-9. doi: 10.3109/21691401.2012.751180. Epub 2013 Jan 22. Artif Cells Nanomed Biotechnol. 2013. PMID: 23336597 Free PMC article.
Lowering of elevated tissue PCO2 in a hemorrhagic shock rat model after reinfusion of a novel nanobiotechnological polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase that is an oxygen and a carbon dioxide carrier with enhanced antioxidant properties.
Bian Y, Wei G, Chang TM. Bian Y, et al. Among authors: Chang TM. Artif Cells Nanomed Biotechnol. 2013 Feb;41(1):60-8. doi: 10.3109/10731199.2013.745291. Artif Cells Nanomed Biotechnol. 2013. PMID: 23347056 Free PMC article.
Cross-linked polyhemoglobin-superoxide dismutase-catalase supplies oxygen without causing blood-brain barrier disruption or brain edema in a rat model of transient global brain ischemia-reperfusion.
Powanda DD, Chang TM. Powanda DD, et al. Among authors: Chang TM. Artif Cells Blood Substit Immobil Biotechnol. 2002 Jan;30(1):23-37. doi: 10.1081/bio-120002725. Artif Cells Blood Substit Immobil Biotechnol. 2002. PMID: 12000224
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