Chang X - Search Results

1

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma.

Chang X, Zhu Y, Shi C, Stewart AK. Chang X, et al. Acta Biochim Biophys Sin (Shanghai). 2014 Mar;46(3):240-53. doi: 10.1093/abbs/gmt142. Epub 2013 Dec 29. Acta Biochim Biophys Sin (Shanghai). 2014. PMID: 24374776 Free PMC article. Review.

2

Mouse Monoclonal Antibodies Generated from Full Length Human Cereblon: Detection of Cereblon Protein in Patients with Multiple Myeloma.

Chang X, Xu Q, Hou Y, Li C, Xu Y, Stewart AK. Chang X, et al. Int J Mol Sci. 2017 Sep 17;18(9):1999. doi: 10.3390/ijms18091999. Int J Mol Sci. 2017. PMID: 28926977 Free PMC article.

3

Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma.

Zhu YX, Braggio E, Shi CX, Kortuem KM, Bruins LA, Schmidt JE, Chang XB, Langlais P, Luo M, Jedlowski P, LaPlant B, Laumann K, Fonseca R, Bergsagel PL, Mikhael J, Lacy M, Champion MD, Stewart AK. Zhu YX, et al. Blood. 2014 Jul 24;124(4):536-45. doi: 10.1182/blood-2014-02-557819. Epub 2014 Jun 9. Blood. 2014. PMID: 24914135 Free PMC article.

4

Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells.

Palaniyandi K, Zhao Q, Chang XB. Palaniyandi K, et al. Int J Biochem Mol Biol. 2011;2(2):155-167. Epub 2011 Apr 22. Int J Biochem Mol Biol. 2011. PMID: 21968975 Free PMC article.

5

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

Zhu YX, Braggio E, Shi CX, Bruins LA, Schmidt JE, Van Wier S, Chang XB, Bjorklund CC, Fonseca R, Bergsagel PL, Orlowski RZ, Stewart AK. Zhu YX, et al. Blood. 2011 Nov 3;118(18):4771-9. doi: 10.1182/blood-2011-05-356063. Epub 2011 Aug 22. Blood. 2011. PMID: 21860026 Free PMC article.

6

What is the functional role of the thalidomide binding protein cereblon?

Chang XB, Stewart AK. Chang XB, et al. Int J Biochem Mol Biol. 2011;2(3):287-94. Epub 2011 Sep 10. Int J Biochem Mol Biol. 2011. PMID: 22003441 Free PMC article.

7

Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival.

Xu Q, Hou YX, Langlais P, Erickson P, Zhu J, Shi CX, Luo M, Zhu Y, Xu Y, Mandarino LJ, Stewart K, Chang XB. Xu Q, et al. BMC Cancer. 2016 May 3;16:297. doi: 10.1186/s12885-016-2331-0. BMC Cancer. 2016. PMID: 27142104 Free PMC article.

8

Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor.

Yang R, Hou YX, Campbell CA, Palaniyandi K, Zhao Q, Bordner AJ, Chang XB. Yang R, et al. Biochim Biophys Acta. 2011 Jul;1808(7):1790-6. doi: 10.1016/j.bbamem.2011.02.004. Epub 2011 Feb 26. Biochim Biophys Acta. 2011. PMID: 21315686 Free PMC article.

9

Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1.

Chang XB. Chang XB. Methods Mol Biol. 2010;596:223-49. doi: 10.1007/978-1-60761-416-6_11. Methods Mol Biol. 2010. PMID: 19949927 Review.

10

The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function.

Yang R, Scavetta R, Chang XB. Yang R, et al. Biochim Biophys Acta. 2008 Feb;1778(2):454-65. doi: 10.1016/j.bbamem.2007.11.010. Epub 2007 Nov 29. Biochim Biophys Acta. 2008. PMID: 18088596 Free PMC article.

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