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19,831 results
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Zinc is a mixed antagonist of homomeric rho 1 gamma-aminobutyric acid-activated channels.
Chang Y, Amin J, Weiss DS. Chang Y, et al. Mol Pharmacol. 1995 Mar;47(3):595-602. Mol Pharmacol. 1995. PMID: 7535381
Mapping the rho1 GABA(C) receptor agonist binding pocket. Constructing a complete model.
Sedelnikova A, Smith CD, Zakharkin SO, Davis D, Weiss DS, Chang Y. Sedelnikova A, et al. Among authors: chang y. J Biol Chem. 2005 Jan 14;280(2):1535-42. doi: 10.1074/jbc.M409908200. Epub 2004 Nov 17. J Biol Chem. 2005. PMID: 15548535
Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function.
Chang Y, Ghansah E, Chen Y, Ye J, Weiss DS. Chang Y, et al. J Neurosci. 2002 Sep 15;22(18):7982-90. doi: 10.1523/JNEUROSCI.22-18-07982.2002. J Neurosci. 2002. PMID: 12223551 Free PMC article.
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism.
Chang Y, Weiss DS. Chang Y, et al. Nat Neurosci. 2002 Nov;5(11):1163-8. doi: 10.1038/nn926. Nat Neurosci. 2002. PMID: 12368804
Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release.
Misaki N, Mao X, Lin YF, Suga S, Li GH, Liu Q, Chang Y, Wang H, Wakui M, Wu J. Misaki N, et al. Among authors: chang y. J Pharmacol Exp Ther. 2007 Aug;322(2):871-8. doi: 10.1124/jpet.107.121129. Epub 2007 May 23. J Pharmacol Exp Ther. 2007. PMID: 17522344
Positive allosteric modulation by ultraviolet irradiation on GABA(A), but not GABA(C), receptors expressed in Xenopus oocytes.
Chang Y, Xie Y, Weiss DS. Chang Y, et al. J Physiol. 2001 Oct 15;536(Pt 2):471-8. doi: 10.1111/j.1469-7793.2001.0471c.xd. J Physiol. 2001. PMID: 11600682 Free PMC article.
Correlation of the apparent affinities and efficacies of gamma-aminobutyric acid(C) receptor agonists.
Chang Y, Covey DF, Weiss DS. Chang Y, et al. Mol Pharmacol. 2000 Dec;58(6):1375-80. doi: 10.1124/mol.58.6.1375. Mol Pharmacol. 2000. PMID: 11093776
Permeability and single channel conductance of human homomeric rho1 GABAC receptors.
Wotring VE, Chang Y, Weiss DS. Wotring VE, et al. Among authors: chang y. J Physiol. 1999 Dec 1;521 Pt 2(Pt 2):327-36. doi: 10.1111/j.1469-7793.1999.00327.x. J Physiol. 1999. PMID: 10581305 Free PMC article.
Allosteric activation mechanism of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid type A receptor revealed by mutation of the conserved M2 leucine.
Chang Y, Weiss DS. Chang Y, et al. Biophys J. 1999 Nov;77(5):2542-51. doi: 10.1016/s0006-3495(99)77089-x. Biophys J. 1999. PMID: 10545355 Free PMC article.
Substitutions of the highly conserved M2 leucine create spontaneously opening rho1 gamma-aminobutyric acid receptors.
Chang Y, Weiss DS. Chang Y, et al. Mol Pharmacol. 1998 Mar;53(3):511-23. doi: 10.1124/mol.53.3.511. Mol Pharmacol. 1998. PMID: 9495819
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