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Changes in the pattern of plasma extracellular vesicles after severe trauma.
Kuravi SJ, Yates CM, Foster M, Harrison P, Hazeldine J, Hampson P, Watson C, Belli A, Midwinter M, Nash GB. Kuravi SJ, et al. PLoS One. 2017 Aug 24;12(8):e0183640. doi: 10.1371/journal.pone.0183640. eCollection 2017. PLoS One. 2017. PMID: 28837705 Free PMC article.
BACKGROUND: Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We thus evaluated the numbers of EV in plasma over 28 days after trauma and evaluated their pro-coagulant and inflammatory effects …
BACKGROUND: Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We t …
Plasma extracellular vesicles released after severe burn injury modulate macrophage phenotype and function.
Willis ML, Mahung C, Wallet SM, Barnett A, Cairns BA, Coleman LG Jr, Maile R. Willis ML, et al. J Leukoc Biol. 2021 Aug 3. doi: 10.1002/JLB.3MIA0321-150RR. Online ahead of print. J Leukoc Biol. 2021. PMID: 34342045
Extracellular vesicles (EVs) have emerged as key regulators of immune function across multiple diseases. ...We have reported that early after severe burn injury HMGB1 and IL-1beta are enriched in plasma EVs. ...
Extracellular vesicles (EVs) have emerged as key regulators of immune function across multiple diseases. ...We have reported t
Thrombin generation and procoagulant microparticle profiles after acute trauma: A prospective cohort study.
Park MS, Xue A, Spears GM, Halling TM, Ferrara MJ, Kuntz MM, Dhillon SK, Jenkins DH, Harmsen WS, Ballman KV, Harrison P, Heit JA. Park MS, et al. J Trauma Acute Care Surg. 2015 Nov;79(5):726-31. doi: 10.1097/TA.0000000000000839. J Trauma Acute Care Surg. 2015. PMID: 26496097 Free PMC article.
To identify potential mechanisms for venous thromboembolism and bleeding after acute trauma, we estimated changes in circulating procoagulant microparticles (MPs) and thrombin activity during hospitalization for trauma. ...CONCLUSION: Although there was no pr …
To identify potential mechanisms for venous thromboembolism and bleeding after acute trauma, we estimated changes in circulati …