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614 results
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Nicotinic receptors at the amino acid level.
Corringer PJ, Le Novère N, Changeux JP. Corringer PJ, et al. Among authors: changeux jp. Annu Rev Pharmacol Toxicol. 2000;40:431-58. doi: 10.1146/annurev.pharmtox.40.1.431. Annu Rev Pharmacol Toxicol. 2000. PMID: 10836143 Review.
The origins of allostery: from personal memories to material for the future.
Changeux JP. Changeux JP. J Mol Biol. 2013 May 13;425(9):1396-406. doi: 10.1016/j.jmb.2013.02.033. Epub 2013 Mar 20. J Mol Biol. 2013. PMID: 23523086
International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.
Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ. Christopoulos A, et al. Among authors: changeux jp. Pharmacol Rev. 2014 Oct;66(4):918-47. doi: 10.1124/pr.114.008862. Pharmacol Rev. 2014. PMID: 25026896
Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation.
Changeux JP, Christopoulos A. Changeux JP, et al. Cell. 2016 Aug 25;166(5):1084-1102. doi: 10.1016/j.cell.2016.08.015. Cell. 2016. PMID: 27565340 Review.
Biased Allostery.
Edelstein SJ, Changeux JP. Edelstein SJ, et al. Among authors: changeux jp. Biophys J. 2016 Sep 6;111(5):902-8. doi: 10.1016/j.bpj.2016.07.044. Biophys J. 2016. PMID: 27602718 Free PMC article.
Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics.
Martin NE, Malik S, Calimet N, Changeux JP, Cecchini M. Martin NE, et al. Among authors: changeux jp. PLoS Comput Biol. 2017 Oct 25;13(10):e1005784. doi: 10.1371/journal.pcbi.1005784. eCollection 2017 Oct. PLoS Comput Biol. 2017. PMID: 29069080 Free PMC article.
Allosteric modulation as a unifying mechanism for receptor function and regulation.
Changeux JP, Christopoulos A. Changeux JP, et al. Diabetes Obes Metab. 2017 Sep;19 Suppl 1:4-21. doi: 10.1111/dom.12959. Diabetes Obes Metab. 2017. PMID: 28880476 Review.
A gating mechanism of pentameric ligand-gated ion channels.
Calimet N, Simoes M, Changeux JP, Karplus M, Taly A, Cecchini M. Calimet N, et al. Among authors: changeux jp. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E3987-96. doi: 10.1073/pnas.1313785110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043807 Free PMC article. Review.
Structure and pharmacology of pentameric receptor channels: from bacteria to brain.
Corringer PJ, Poitevin F, Prevost MS, Sauguet L, Delarue M, Changeux JP. Corringer PJ, et al. Among authors: changeux jp. Structure. 2012 Jun 6;20(6):941-56. doi: 10.1016/j.str.2012.05.003. Structure. 2012. PMID: 22681900 Review.
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Nury H, Van Renterghem C, Weng Y, Tran A, Baaden M, Dufresne V, Changeux JP, Sonner JM, Delarue M, Corringer PJ. Nury H, et al. Among authors: changeux jp. Nature. 2011 Jan 20;469(7330):428-31. doi: 10.1038/nature09647. Nature. 2011. PMID: 21248852
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