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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.
Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. Kuba K, et al. Among authors: chappell m. Nat Med. 2005 Aug;11(8):875-9. doi: 10.1038/nm1267. Epub 2005 Jul 10. Nat Med. 2005. PMID: 16007097 Free PMC article.
Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. Crackower MA, et al. Among authors: chappell mc. Nature. 2002 Jun 20;417(6891):822-8. doi: 10.1038/nature00786. Nature. 2002. PMID: 12075344
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia.
Jia HP, Look DC, Tan P, Shi L, Hickey M, Gakhar L, Chappell MC, Wohlford-Lenane C, McCray PB Jr. Jia HP, et al. Among authors: chappell mc. Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L84-96. doi: 10.1152/ajplung.00071.2009. Epub 2009 May 1. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19411314 Free PMC article.
COVID-19, ACE2, and the cardiovascular consequences.
South AM, Diz DI, Chappell MC. South AM, et al. Among authors: chappell mc. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1084-H1090. doi: 10.1152/ajpheart.00217.2020. Epub 2020 Mar 31. Am J Physiol Heart Circ Physiol. 2020. PMID: 32228252 Free PMC article.
619 results