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In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-one (indacaterol), a novel inhaled beta(2) adrenoceptor agonist with a 24-h duration of action.
Battram C, Charlton SJ, Cuenoud B, Dowling MR, Fairhurst RA, Farr D, Fozard JR, Leighton-Davies JR, Lewis CA, McEvoy L, Turner RJ, Trifilieff A. Battram C, et al. Among authors: charlton sj. J Pharmacol Exp Ther. 2006 May;317(2):762-70. doi: 10.1124/jpet.105.098251. Epub 2006 Jan 24. J Pharmacol Exp Ther. 2006. PMID: 16434564
SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor.
Bradley ME, Bond ME, Manini J, Brown Z, Charlton SJ. Bradley ME, et al. Among authors: charlton sj. Br J Pharmacol. 2009 Sep;158(1):328-38. doi: 10.1111/j.1476-5381.2009.00182.x. Epub 2009 Apr 24. Br J Pharmacol. 2009. PMID: 19422399 Free PMC article.
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