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Evaluation of the mass balance assumption with respect to the two-resistance model of intestinal absorption by using in situ single-pass intestinal perfusion of theophylline in rats.
Dackson K, Stone JA, Palin KJ, Charman WN. Dackson K, et al. J Pharm Sci. 1992 Apr;81(4):321-5. doi: 10.1002/jps.2600810404. J Pharm Sci. 1992. PMID: 1501064
Computational prediction of formulation strategies for beyond-rule-of-5 compounds.
Bergström CAS, Charman WN, Porter CJH. Bergström CAS, et al. Adv Drug Deliv Rev. 2016 Jun 1;101:6-21. doi: 10.1016/j.addr.2016.02.005. Epub 2016 Feb 27. Adv Drug Deliv Rev. 2016. PMID: 26928657 Review.
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Charman SA, Arbe-Barnes S, Bathurst IC, Brun R, Campbell M, Charman WN, Chiu FC, Chollet J, Craft JC, Creek DJ, Dong Y, Matile H, Maurer M, Morizzi J, Nguyen T, Papastogiannidis P, Scheurer C, Shackleford DM, Sriraghavan K, Stingelin L, Tang Y, Urwyler H, Wang X, White KL, Wittlin S, Zhou L, Vennerstrom JL. Charman SA, et al. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4400-5. doi: 10.1073/pnas.1015762108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300861 Free PMC article.
The role of lecithin degradation on the pH dependent stability of halofantrine encapsulated fat nano-emulsions.
Haidar I, Harding IH, Bowater IC, Eldridge DS, Charman WN. Haidar I, et al. Among authors: charman wn. Int J Pharm. 2017 Aug 7;528(1-2):524-535. doi: 10.1016/j.ijpharm.2017.06.040. Epub 2017 Jun 13. Int J Pharm. 2017. PMID: 28619452
Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies.
Han S, Quach T, Hu L, Wahab A, Charman WN, Stella VJ, Trevaskis NL, Simpson JS, Porter CJ. Han S, et al. J Control Release. 2014 Mar 10;177:1-10. doi: 10.1016/j.jconrel.2013.12.031. Epub 2014 Jan 5. J Control Release. 2014. PMID: 24398334
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