Search Page

1

Cite

Share

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. Jinek M, et al. Among authors: charpentier e. Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28. Science. 2012. PMID: 22745249 Free PMC article.

Cite

Share

2

Cite

Share

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems.

Fonfara I, Le Rhun A, Chylinski K, Makarova KS, Lécrivain AL, Bzdrenga J, Koonin EV, Charpentier E. Fonfara I, et al. Among authors: charpentier e. Nucleic Acids Res. 2014 Feb;42(4):2577-90. doi: 10.1093/nar/gkt1074. Epub 2013 Nov 22. Nucleic Acids Res. 2014. PMID: 24270795 Free PMC article.

Cite

Share

3

Cite

Share

Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Jinek M, et al. Among authors: charpentier e. Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6. Science. 2014. PMID: 24505130 Free PMC article.

Cite

Share

4

Cite

Share

Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Doudna JA, Charpentier E. Doudna JA, et al. Among authors: charpentier e. Science. 2014 Nov 28;346(6213):1258096. doi: 10.1126/science.1258096. Science. 2014. PMID: 25430774 Review.

Cite

Share

5

Cite

Share

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches.

Bratovič M, Fonfara I, Chylinski K, Gálvez EJC, Sullivan TJ, Boerno S, Timmermann B, Boettcher M, Charpentier E. Bratovič M, et al. Among authors: charpentier e. Nat Chem Biol. 2020 May;16(5):587-595. doi: 10.1038/s41589-020-0490-4. Epub 2020 Mar 2. Nat Chem Biol. 2020. PMID: 32123387

Cite

Share

6

Cite

Share

McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR.

Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T. Fuhrmann J, et al. Among authors: charpentier e. Science. 2009 Jun 5;324(5932):1323-7. doi: 10.1126/science.1170088. Science. 2009. PMID: 19498169

Cite

Share

7

Cite

Share

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity.

Charpentier E, Richter H, van der Oost J, White MF. Charpentier E, et al. FEMS Microbiol Rev. 2015 May;39(3):428-41. doi: 10.1093/femsre/fuv023. Epub 2015 May 19. FEMS Microbiol Rev. 2015. PMID: 25994611 Free PMC article. Review.

Cite

Share

8

Cite

Share

Lysogenic transfer of group A Streptococcus superantigen gene among Streptococci.

Vojtek I, Pirzada ZA, Henriques-Normark B, Mastny M, Janapatla RP, Charpentier E. Vojtek I, et al. Among authors: charpentier e. J Infect Dis. 2008 Jan 15;197(2):225-34. doi: 10.1086/524687. J Infect Dis. 2008. PMID: 18179387 Free PMC article.

Cite

Share

9

Cite

Share

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E. Deltcheva E, et al. Among authors: charpentier e. Nature. 2011 Mar 31;471(7340):602-7. doi: 10.1038/nature09886. Nature. 2011. PMID: 21455174 Free PMC article.

Cite

Share

10

Cite

Share

Small RNAs in streptococci.

Le Rhun A, Charpentier E. Le Rhun A, et al. Among authors: charpentier e. RNA Biol. 2012 Apr;9(4):414-26. doi: 10.4161/rna.20104. Epub 2012 Apr 1. RNA Biol. 2012. PMID: 22546939 Review.

Cite

Share