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The adaptor Lnk (SH2B3): an emerging regulator in vascular cells and a link between immune and inflammatory signaling.
Devallière J, Charreau B. Devallière J, et al. Among authors: charreau b. Biochem Pharmacol. 2011 Nov 15;82(10):1391-402. doi: 10.1016/j.bcp.2011.06.023. Epub 2011 Jun 24. Biochem Pharmacol. 2011. PMID: 21723852 Review.
Association of glucocorticoids and cyclosporin A or rapamycin prevents E-selectin and IL-8 expression during LPS- and TNFalpha-mediated endothelial cell activation.
Charreau B, Coupel S, Goret F, Pourcel C, Soulillou JP. Charreau B, et al. Transplantation. 2000 Mar 15;69(5):945-53. doi: 10.1097/00007890-200003150-00047. Transplantation. 2000. PMID: 10755555
Cyclosporine inhibits class II major histocompatibility antigen presentation by xenogeneic endothelial cells to human T lymphocytes by altering expression of the class II transcriptional activator gene.
Charreau B, Coupel S, Boulday G, Soulillou JP. Charreau B, et al. Transplantation. 2000 Jul 27;70(2):354-61. doi: 10.1097/00007890-200007270-00021. Transplantation. 2000. PMID: 10933163
Transcriptional up-regulation of the signaling regulatory protein LNK in activated endothelial cells.
Boulday G, Coulon F, Fraser CC, Soulillou JP, Charreau B. Boulday G, et al. Among authors: charreau b. Transplantation. 2002 Nov 15;74(9):1352-4. doi: 10.1097/00007890-200211150-00026. Transplantation. 2002. PMID: 12451278
RhoA activation mediates phosphatidylinositol 3-kinase-dependent proliferation of human vascular endothelial cells: an alloimmune mechanism of chronic allograft nephropathy.
Coupel S, Leboeuf F, Boulday G, Soulillou JP, Charreau B. Coupel S, et al. Among authors: charreau b. J Am Soc Nephrol. 2004 Sep;15(9):2429-39. doi: 10.1097/01.ASN.0000138237.42675.45. J Am Soc Nephrol. 2004. PMID: 15339992
Vascular endothelial cells evade apoptosis triggered by human leukocyte antigen-DR ligation mediated by allospecific antibodies.
Le Bas-Bernardet S, Coupel S, Chauveau A, Soulillou JP, Charreau B. Le Bas-Bernardet S, et al. Among authors: charreau b. Transplantation. 2004 Dec 27;78(12):1729-39. doi: 10.1097/01.tp.0000147339.31581.99. Transplantation. 2004. PMID: 15614145
BACKGROUND: Human leukocyte antigen (HLA)-DR ligation mediates cell death of antigen-presenting cells (APC), including mature B cells, macrophages, and dendritic cells. ...RESULTS: Even with optimal stimulation, the expression of HLA-DR on interferon (IFN)-gamma-treated EC …
BACKGROUND: Human leukocyte antigen (HLA)-DR ligation mediates cell death of antigen-presenting cells (APC), including mature B cells …
The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways.
Fitau J, Boulday G, Coulon F, Quillard T, Charreau B. Fitau J, et al. Among authors: charreau b. J Biol Chem. 2006 Jul 21;281(29):20148-59. doi: 10.1074/jbc.M510997200. Epub 2006 Apr 27. J Biol Chem. 2006. PMID: 16644735
Lnk, with APS and SH2-B (Src homology 2-B), belongs to a family of SH2-containing proteins with potential adaptor functions. ...
Lnk, with APS and SH2-B (Src homology 2-B), belongs to a family of SH2-containing proteins with potential adaptor functions. . …
[The adaptor protein Lnk modulates endothelial cell activation].
Fitau J, Boulday G, Coulon F, Charreau B. Fitau J, et al. Among authors: charreau b. Nephrol Ther. 2005 Oct;1(4):228-33. doi: 10.1016/j.nephro.2005.06.010. Epub 2005 Aug 26. Nephrol Ther. 2005. PMID: 16895689 French.
Lnk is an adaptator protein involved in B lymphocytes and platelet differentiation and in T lymphocyte activation. We previously reported on Lnk expression and regulation in endothelial cells (ECs) upon activation. ...
Lnk is an adaptator protein involved in B lymphocytes and platelet differentiation and in T lymphocyte activation. We previously repo …
Impaired Notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis.
Quillard T, Coupel S, Coulon F, Fitau J, Chatelais M, Cuturi MC, Chiffoleau E, Charreau B. Quillard T, et al. Among authors: charreau b. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2258-65. doi: 10.1161/ATVBAHA.108.174995. Epub 2008 Sep 18. Arterioscler Thromb Vasc Biol. 2008. PMID: 18802018
The C-type lectin-like receptor CLEC-1, expressed by myeloid cells and endothelial cells, is up-regulated by immunoregulatory mediators and moderates T cell activation.
Thebault P, Lhermite N, Tilly G, Le Texier L, Quillard T, Heslan M, Anegon I, Soulillou JP, Brouard S, Charreau B, Cuturi MC, Chiffoleau E. Thebault P, et al. Among authors: charreau b. J Immunol. 2009 Sep 1;183(5):3099-108. doi: 10.4049/jimmunol.0803767. Epub 2009 Aug 10. J Immunol. 2009. PMID: 19667084
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