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Hypersensitivity to clinically useful alkylating agents and radiation in poly(ADP-ribose) polymerase-deficient cell lines.
Chatterjee S, Cheng MF, Berger NA. Chatterjee S, et al. Cancer Commun. 1990;2(12):401-7. doi: 10.3727/095535490820873958. Cancer Commun. 1990. PMID: 1702304
Mutant V79 Chinese hamster cell lines, deficient in poly(ADP-ribose) polymerase activity, were previously shown to be significantly resistant to etoposide, a topoisomerase II inhibitor, and hypersensitive to camptothecin, a topoisomerase I inhibitor (Chatterjee, S.; …
Mutant V79 Chinese hamster cell lines, deficient in poly(ADP-ribose) polymerase activity, were previously shown to be significantly resistan …
Alkylating agent hypersensitivity in poly(adenosine diphosphate-ribose) polymerase deficient cell lines.
Chatterjee S, Cheng MF, Berger SJ, Berger NA. Chatterjee S, et al. Cancer Commun. 1991 Mar;3(3):71-5. doi: 10.3727/095535491820873551. Cancer Commun. 1991. PMID: 1900426
Starting with the V79 cell line, two poly(ADP-ribose) polymerase deficient mutants, designated ADPRT 54 and ADPRT 351, had been shown to be hypersensitive to x- and UV-irradiation and to topoisomerase I inhibitors but to be resistant to topoisomerase II inhibitors (Chatterjee …
Starting with the V79 cell line, two poly(ADP-ribose) polymerase deficient mutants, designated ADPRT 54 and ADPRT 351, had been shown to be …
5,737 results