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Decreased phenylalanine uptake and turnover in patients with vitiligo.
Schallreuter KU, Chavan B, Rokos H, Hibberts N, Panske A, Wood JM. Schallreuter KU, et al. Among authors: chavan b. Mol Genet Metab. 2005 Dec;86 Suppl 1:S27-33. doi: 10.1016/j.ymgme.2005.07.023. Epub 2005 Sep 6. Mol Genet Metab. 2005. PMID: 16143555 Review.
A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin.
Spencer JD, Chavan B, Marles LK, Kauser S, Rokos H, Schallreuter KU. Spencer JD, et al. Among authors: chavan b. J Endocrinol. 2005 Nov;187(2):293-302. doi: 10.1677/joe.1.06275. J Endocrinol. 2005. PMID: 16293777
Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus.
Schallreuter KU, Rübsam K, Chavan B, Zothner C, Gillbro JM, Spencer JD, Wood JM. Schallreuter KU, et al. Among authors: chavan b. Biochem Biophys Res Commun. 2006 Mar 31;342(1):145-52. doi: 10.1016/j.bbrc.2006.01.124. Epub 2006 Feb 3. Biochem Biophys Res Commun. 2006. PMID: 16480945
Estrogens can contribute to hydrogen peroxide generation and quinone-mediated DNA damage in peripheral blood lymphocytes from patients with vitiligo.
Schallreuter KU, Chiuchiarelli G, Cemeli E, Elwary SM, Gillbro JM, Spencer JD, Rokos H, Panske A, Chavan B, Wood JM, Anderson D. Schallreuter KU, et al. Among authors: chavan b. J Invest Dermatol. 2006 May;126(5):1036-42. doi: 10.1038/sj.jid.5700257. J Invest Dermatol. 2006. PMID: 16528352
For this purpose, 20 Caucasian patients were grouped in treated responders (group A, n=11) and untreated active/acute disease (group B, n=9) and compared to Caucasian healthy controls (group C, n=7). ...
For this purpose, 20 Caucasian patients were grouped in treated responders (group A, n=11) and untreated active/acute disease (group B
The vesicular acetylcholine transporter is present in melanocytes and keratinocytes in the human epidermis.
Elwary SM, Chavan B, Schallreuter KU. Elwary SM, et al. Among authors: chavan b. J Invest Dermatol. 2006 Aug;126(8):1879-84. doi: 10.1038/sj.jid.5700268. Epub 2006 Jun 8. J Invest Dermatol. 2006. PMID: 16763548
GTP cyclohydrolase feedback regulatory protein controls cofactor 6-tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes.
Chavan B, Gillbro JM, Rokos H, Schallreuter KU. Chavan B, et al. J Invest Dermatol. 2006 Nov;126(11):2481-9. doi: 10.1038/sj.jid.5700425. Epub 2006 Jun 15. J Invest Dermatol. 2006. PMID: 16778797
Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo.
Schallreuter KU, Rübsam K, Gibbons NC, Maitland DJ, Chavan B, Zothner C, Rokos H, Wood JM. Schallreuter KU, et al. Among authors: chavan b. J Invest Dermatol. 2008 Apr;128(4):808-15. doi: 10.1038/sj.jid.5701100. Epub 2007 Oct 18. J Invest Dermatol. 2008. PMID: 17943184
In normal healthy human skin, methionine sulfoxide reductases A and B specifically reduce methionine sulfoxides (S) and (R), respectively, back to L-methionine consequently repairing oxidatively damaged proteins and peptides. ...
In normal healthy human skin, methionine sulfoxide reductases A and B specifically reduce methionine sulfoxides (S) and (R), respecti …
Regulation of melanogenesis--controversies and new concepts.
Schallreuter KU, Kothari S, Chavan B, Spencer JD. Schallreuter KU, et al. Among authors: chavan b. Exp Dermatol. 2008 May;17(5):395-404. doi: 10.1111/j.1600-0625.2007.00675.x. Epub 2007 Dec 31. Exp Dermatol. 2008. PMID: 18177348 Review.
Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo?
Wood JM, Gibbons NC, Chavan B, Schallreuter KU. Wood JM, et al. Among authors: chavan b. Exp Dermatol. 2008 Apr;17(4):366-71. doi: 10.1111/j.1600-0625.2008.00699.x. Exp Dermatol. 2008. PMID: 18315617
H(2)O(2) increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo.
Chavan B, Beazley W, Wood JM, Rokos H, Ichinose H, Schallreuter KU. Chavan B, et al. J Inherit Metab Dis. 2009 Feb;32(1):86-94. doi: 10.1007/s10545-008-0971-1. Epub 2008 Dec 22. J Inherit Metab Dis. 2009. PMID: 19101819
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