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Chemokine-containing exosomes are released from heat-stressed tumor cells via lipid raft-dependent pathway and act as efficient tumor vaccine.
Chen T, Guo J, Yang M, Zhu X, Cao X. Chen T, et al. J Immunol. 2011 Feb 15;186(4):2219-28. doi: 10.4049/jimmunol.1002991. Epub 2011 Jan 17. J Immunol. 2011. PMID: 21242526
Moreover, the production of chemokine-containing HS-TEX could be inhibited by ATP inhibitor, calcium chelator, and cholesterol scavenger, indicating that the mobilization of chemokines into exosomes was ATP- and calcium-dependent and via a lipid …
Moreover, the production of chemokine-containing HS-TEX could be inhibited by ATP inhibitor, calcium chelator, and cholesterol …