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Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
Rajamanickam S, Velmurugan B, Kaur M, Singh RP, Agarwal R. Rajamanickam S, et al. Cancer Res. 2010 Mar 15;70(6):2368-78. doi: 10.1158/0008-5472.CAN-09-3249. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215518 Free PMC article.
Accordingly, here we assessed chemopreventive efficacy and associated mechanisms of long-term silibinin feeding on spontaneous intestinal tumorigenesis in the APC(min/+) mice model. ...These results show for the first time the efficacy and assoc …
Accordingly, here we assessed chemopreventive efficacy and associated mechanisms of long-term silibinin feeding on spontaneous …
Evaluation of the cancer chemopreventive efficacy of silibinin in genetic mouse models of prostate and intestinal carcinogenesis: relationship with silibinin levels.
Verschoyle RD, Greaves P, Patel K, Marsden DA, Brown K, Steward WP, Gescher AJ. Verschoyle RD, et al. Eur J Cancer. 2008 Apr;44(6):898-906. doi: 10.1016/j.ejca.2008.02.020. Epub 2008 Mar 17. Eur J Cancer. 2008. PMID: 18343654
Silibinin, a flavonolignan from milk thistle seeds, possesses cancer chemopreventive properties in rodent models of carcinogenesis. ...Mice received silibinin or silipide with their diet (0.2% silibinin equivalents) from weaning. ...
Silibinin, a flavonolignan from milk thistle seeds, possesses cancer chemopreventive properties in rodent models of carcino …