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CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma.
Li Z, Wang B, Gu S, Jiang P, Sahu A, Chen CH, Han T, Shi S, Wang X, Traugh N, Liu H, Liu Y, Wu Q, Brown M, Xiao T, Boland GM, Shirley Liu X. Li Z, et al. Among authors: chen ch. Genomics Proteomics Bioinformatics. 2020 Feb;18(1):26-40. doi: 10.1016/j.gpb.2020.02.002. Epub 2020 May 13. Genomics Proteomics Bioinformatics. 2020. PMID: 32413516 Free PMC article.
Sequence determinants of improved CRISPR sgRNA design.
Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Xu H, et al. Among authors: chen ch. Genome Res. 2015 Aug;25(8):1147-57. doi: 10.1101/gr.191452.115. Epub 2015 Jun 10. Genome Res. 2015. PMID: 26063738 Free PMC article.
CRISPR-DO for genome-wide CRISPR design and optimization.
Ma J, Köster J, Qin Q, Hu S, Li W, Chen C, Cao Q, Wang J, Mei S, Liu Q, Xu H, Liu XS. Ma J, et al. Bioinformatics. 2016 Nov 1;32(21):3336-3338. doi: 10.1093/bioinformatics/btw476. Epub 2016 Jul 10. Bioinformatics. 2016. PMID: 27402906 Free PMC article.
Improved design and analysis of CRISPR knockout screens.
Chen CH, Xiao T, Xu H, Jiang P, Meyer CA, Li W, Brown M, Liu XS. Chen CH, et al. Bioinformatics. 2018 Dec 1;34(23):4095-4101. doi: 10.1093/bioinformatics/bty450. Bioinformatics. 2018. PMID: 29868757 Free PMC article.
Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute.
Wang B, Wang M, Zhang W, Xiao T, Chen CH, Wu A, Wu F, Traugh N, Wang X, Li Z, Mei S, Cui Y, Shi S, Lipp JJ, Hinterndorfer M, Zuber J, Brown M, Li W, Liu XS. Wang B, et al. Among authors: chen ch. Nat Protoc. 2019 Mar;14(3):756-780. doi: 10.1038/s41596-018-0113-7. Epub 2019 Feb 1. Nat Protoc. 2019. PMID: 30710114 Free PMC article.
Deciphering essential cistromes using genome-wide CRISPR screens.
Fei T, Li W, Peng J, Xiao T, Chen CH, Wu A, Huang J, Zang C, Liu XS, Brown M. Fei T, et al. Among authors: chen ch. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25186-25195. doi: 10.1073/pnas.1908155116. Epub 2019 Nov 14. Proc Natl Acad Sci U S A. 2019. PMID: 31727847 Free PMC article.
8,768 results