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Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage.
Muniyappa R, Lee S, Chen H, Quon MJ. Muniyappa R, et al. Among authors: chen h. Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E15-26. doi: 10.1152/ajpendo.00645.2007. Epub 2007 Oct 23. Am J Physiol Endocrinol Metab. 2008. PMID: 17957034 Review.
QUICKI is a useful index of insulin sensitivity in subjects with hypertension.
Chen H, Sullivan G, Yue LQ, Katz A, Quon MJ. Chen H, et al. Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E804-12. doi: 10.1152/ajpendo.00330.2002. Am J Physiol Endocrinol Metab. 2003. PMID: 12678026 No abstract available.
Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic glucose clamps in rhesus monkeys.
Lee HW, Muniyappa R, Yan X, Yue LQ, Linden EH, Chen H, Hansen BC, Quon MJ. Lee HW, et al. Among authors: chen h. Endocrinology. 2011 Feb;152(2):414-23. doi: 10.1210/en.2010-1164. Epub 2011 Jan 5. Endocrinology. 2011. PMID: 21209021 Free PMC article.
Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps.
Singal P, Muniyappa R, Chisholm R, Hall G, Chen H, Quon MJ, Mather KJ. Singal P, et al. Among authors: chen h. Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E229-36. doi: 10.1152/ajpendo.00603.2009. Epub 2009 Nov 17. Am J Physiol Endocrinol Metab. 2010. PMID: 19920219 Free PMC article. Clinical Trial.
After a constant insulin infusion is initiated, determination of steady-state conditions for glucose infusion rates (GIR) typically requires >or=3 h. ...
After a constant insulin infusion is initiated, determination of steady-state conditions for glucose infusion rates (GIR) typically requires …
Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats.
Muniyappa R, Chen H, Muzumdar RH, Einstein FH, Yan X, Yue LQ, Barzilai N, Quon MJ. Muniyappa R, et al. Among authors: chen h. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1023-9. doi: 10.1152/ajpendo.00397.2009. Epub 2009 Aug 25. Am J Physiol Endocrinol Metab. 2009. PMID: 19706785 Free PMC article.
Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice.
Lee S, Muniyappa R, Yan X, Chen H, Yue LQ, Hong EG, Kim JK, Quon MJ. Lee S, et al. Among authors: chen h. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E261-70. doi: 10.1152/ajpendo.00676.2007. Epub 2007 Nov 14. Am J Physiol Endocrinol Metab. 2008. PMID: 18003716
Letter re: Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation.
Karne RJ, Chen H, Sullivan G, Quon MJ. Karne RJ, et al. Among authors: chen h. J Clin Endocrinol Metab. 2005 Jul;90(7):4418-9; author reply 4419. doi: 10.1210/jc.2005-0528. J Clin Endocrinol Metab. 2005. PMID: 16002414 No abstract available.
High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance.
Chen H, Karne RJ, Hall G, Campia U, Panza JA, Cannon RO 3rd, Wang Y, Katz A, Levine M, Quon MJ. Chen H, et al. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H137-45. doi: 10.1152/ajpheart.00768.2005. Epub 2005 Aug 26. Am J Physiol Heart Circ Physiol. 2006. PMID: 16126809 Clinical Trial.
Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells.
Iantorno M, Chen H, Kim JA, Tesauro M, Lauro D, Cardillo C, Quon MJ. Iantorno M, et al. Among authors: chen h. Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E756-64. doi: 10.1152/ajpendo.00570.2006. Epub 2006 Nov 14. Am J Physiol Endocrinol Metab. 2007. PMID: 17106060
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