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Toxicological significance of azo dye metabolism by human intestinal microbiota.
Feng J, Cerniglia CE, Chen H. Feng J, et al. Among authors: chen h. Front Biosci (Elite Ed). 2012 Jan 1;4:568-86. doi: 10.2741/400. Front Biosci (Elite Ed). 2012. PMID: 22201895 Free PMC article. Review.
Azoreductase in Staphylococcus aureus.
Zou W, Cerniglia CE, Chen H. Zou W, et al. Among authors: chen h. Curr Protoc Toxicol. 2009;Chapter 4:Unit4.28. doi: 10.1002/0471140856.tx0428s41. Curr Protoc Toxicol. 2009. PMID: 23045013
Azoreductase(s) catalyze a NAD(P)H-dependent reaction in bacteria to metabolize azo dyes to colorless aromatic amines. Azoreductases from bacteria represent a novel family of enzymes with little similarity to other reductases. ...
Azoreductase(s) catalyze a NAD(P)H-dependent reaction in bacteria to metabolize azo dyes to colorless aromatic amines. Azoreductases …
Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24.
Chen H, Feng J, Kweon O, Xu H, Cerniglia CE. Chen H, et al. BMC Biochem. 2010 Mar 16;11:13. doi: 10.1186/1471-2091-11-13. BMC Biochem. 2010. PMID: 20233432 Free PMC article.
Phylogenetic analysis shows that AzoB belongs to the flavin-free azoreductase group which has a key fingerprint motif GXXGXXG for NAD(P)H binding at the N-terminus of the amino acid sequences. ...
Phylogenetic analysis shows that AzoB belongs to the flavin-free azoreductase group which has a key fingerprint motif GXXGXXG for NAD(P)H
Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.
Xu H, Heinze TM, Chen S, Cerniglia CE, Chen H. Xu H, et al. Among authors: chen s, chen h. Appl Environ Microbiol. 2007 Dec;73(23):7759-62. doi: 10.1128/AEM.01410-07. Epub 2007 Oct 12. Appl Environ Microbiol. 2007. PMID: 17933925 Free PMC article.
Recent advances in azo dye degrading enzyme research.
Chen H. Chen H. Curr Protein Pept Sci. 2006 Apr;7(2):101-11. doi: 10.2174/138920306776359786. Curr Protein Pept Sci. 2006. PMID: 16611136 Free PMC article. Review.
These dyes are mainly metabolized by bacteria to colorless aromatic amines, some of which are carcinogenic, by azoreductases that catalyze a NAD(P)H-dependent reduction. ...The first class of azoreductases is monomeric flavin-free enzymes containing a putative NAD(P)H
These dyes are mainly metabolized by bacteria to colorless aromatic amines, some of which are carcinogenic, by azoreductases that catalyze a …
Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein.
Chen H, Hopper SL, Cerniglia CE. Chen H, et al. Microbiology (Reading). 2005 May;151(Pt 5):1433-1441. doi: 10.1099/mic.0.27805-0. Microbiology (Reading). 2005. PMID: 15870453 Free PMC article.
Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis.
Chen H, Wang RF, Cerniglia CE. Chen H, et al. Protein Expr Purif. 2004 Apr;34(2):302-10. doi: 10.1016/j.pep.2003.12.016. Protein Expr Purif. 2004. PMID: 15003265 Free PMC article.
Microarray method to monitor 40 intestinal bacterial species in the study of azo dye reduction.
Wang RF, Chen H, Paine DD, Cerniglia CE. Wang RF, et al. Among authors: chen h. Biosens Bioelectron. 2004 Nov 1;20(4):699-705. doi: 10.1016/j.bios.2004.04.011. Biosens Bioelectron. 2004. PMID: 15522584 Free PMC article.
Evaluation of metabolism of azo dyes and their effects on Staphylococcus aureus metabolome.
Sun J, Jin J, Beger RD, Cerniglia CE, Chen H. Sun J, et al. Among authors: chen h. J Ind Microbiol Biotechnol. 2017 Oct;44(10):1471-1481. doi: 10.1007/s10295-017-1970-8. Epub 2017 Aug 7. J Ind Microbiol Biotechnol. 2017. PMID: 28786013 Free PMC article.
Effect of smokeless tobacco products on human oral bacteria growth and viability.
Liu M, Jin J, Pan H, Feng J, Cerniglia CE, Yang M, Chen H. Liu M, et al. Among authors: chen h. Anaerobe. 2016 Dec;42:152-161. doi: 10.1016/j.anaerobe.2016.10.006. Epub 2016 Oct 15. Anaerobe. 2016. PMID: 27756619 Free PMC article.
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