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826 results
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Identification of human liver cytochrome P450s involved in the microsomal metabolism of the antihistaminic drug loratadine.
Yumibe N, Huie K, Chen KJ, Clement RP, Cayen MN. Yumibe N, et al. Among authors: chen kj. Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):420. doi: 10.1159/000237063. Int Arch Allergy Immunol. 1995. PMID: 7613198 No abstract available.
Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2.
Krishna G, Chen K, Lin C, Nomeir AA. Krishna G, et al. Int J Pharm. 2001 Jul 3;222(1):77-89. doi: 10.1016/s0378-5173(01)00698-6. Int J Pharm. 2001. PMID: 11404034
Analogues of 1-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo-[5,6]-cyclohepta [1,2-b]pyridin-11-yl)piperidine as inhibitors of farnesyl protein transferase.
Afonso A, Weinstein J, Kelly J, Wolin R, Rosenblum SB, Connolly M, Guzi T, James L, Carr D, Patton R, Bishop WR, Kirshmeier P, Liu M, Heimark L, Chen KJ, Nomeir AA. Afonso A, et al. Among authors: chen kj. Bioorg Med Chem. 1999 Sep;7(9):1845-55. doi: 10.1016/s0968-0896(99)00103-0. Bioorg Med Chem. 1999. PMID: 10530932
Inhibitors of farnesyl protein transferase. 4-Amido, 4-carbamoyl, and 4-carboxamido derivatives of 1-(8-chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine and 1-(3-bromo-8-chloro-6,11- dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine.
Mallams AK, Rossman RR, Doll RJ, Girijavallabhan VM, Ganguly AK, Petrin J, Wang L, Patton R, Bishop WR, Carr DM, Kirschmeier P, Catino JJ, Bryant MS, Chen KJ, Korfmacher WA, Nardo C, Wang S, Nomeir AA, Lin CC, Li Z, Chen J, Lee S, Dell J, Lipari P, Liu M, et al. Mallams AK, et al. Among authors: chen j, chen kj. J Med Chem. 1998 Mar 12;41(6):877-93. doi: 10.1021/jm970462w. J Med Chem. 1998. PMID: 9526562
Structure-activity relationship of 3-substituted N-(pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene )- piperidine inhibitors of farnesyl-protein transferase: design and synthesis of in vivo active antitumor compounds.
Njoroge FG, Vibulbhan B, Rane DF, Bishop WR, Petrin J, Patton R, Bryant MS, Chen KJ, Nomeir AA, Lin CC, Liu M, King I, Chen J, Lee S, Yaremko B, Dell J, Lipari P, Malkowski M, Li Z, Catino J, Doll RJ, Girijavallabhan V, Ganguly AK. Njoroge FG, et al. Among authors: chen j, chen kj. J Med Chem. 1997 Dec 19;40(26):4290-301. doi: 10.1021/jm970464g. J Med Chem. 1997. PMID: 9435898
Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
Yumibe N, Huie K, Chen KJ, Snow M, Clement RP, Cayen MN. Yumibe N, et al. Among authors: chen kj. Biochem Pharmacol. 1996 Jan 26;51(2):165-72. doi: 10.1016/0006-2952(95)02169-8. Biochem Pharmacol. 1996. PMID: 8615885
Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency.
Arasappan A, Njoroge FG, Chan TY, Bennett F, Bogen SL, Chen K, Gu H, Hong L, Jao E, Liu YT, Lovey RG, Parekh T, Pike RE, Pinto P, Santhanam B, Venkatraman S, Vaccaro H, Wang H, Yang X, Zhu Z, Mckittrick B, Saksena AK, Girijavallabhan V, Pichardo J, Butkiewicz N, Ingram R, Malcolm B, Prongay A, Yao N, Marten B, Madison V, Kemp S, Levy O, Lim-Wilby M, Tamura S, Ganguly AK. Arasappan A, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4180-4. doi: 10.1016/j.bmcl.2005.06.091. Bioorg Med Chem Lett. 2005. PMID: 16087332
Clinical application of a surgical navigation system for the retrieval of fractured dental needles.
Chen KJ, Lo WF, Chen I, Chen MYC. Chen KJ, et al. Br J Oral Maxillofac Surg. 2020 Dec 8:S0266-4356(20)30956-6. doi: 10.1016/j.bjoms.2020.12.002. Online ahead of print. Br J Oral Maxillofac Surg. 2020. PMID: 33461821 No abstract available.
Generating Giant Vortex in a Fermi Superfluid via Spin-Orbital-Angular-Momentum Coupling.
Chen KJ, Wu F, Peng SG, Yi W, He L. Chen KJ, et al. Phys Rev Lett. 2020 Dec 31;125(26):260407. doi: 10.1103/PhysRevLett.125.260407. Phys Rev Lett. 2020. PMID: 33449717
Pore Engineering for One-Step Ethylene Purification from a Three-Component Hydrocarbon Mixture.
Zhu B, Cao JW, Mukherjee S, Pham T, Zhang T, Wang T, Jiang X, Forrest KA, Zaworotko MJ, Chen KJ. Zhu B, et al. Among authors: chen kj. J Am Chem Soc. 2021 Jan 13. doi: 10.1021/jacs.0c11247. Online ahead of print. J Am Chem Soc. 2021. PMID: 33439004
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