Chen L - Search Results

1

Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features.

Chen L, Li J, Luo C, Liu H, Xu W, Chen G, Liew OW, Zhu W, Puah CM, Shen X, Jiang H. Chen L, et al. Among authors: chen g. Bioorg Med Chem. 2006 Dec 15;14(24):8295-306. doi: 10.1016/j.bmc.2006.09.014. Epub 2006 Oct 12. Bioorg Med Chem. 2006. PMID: 17046271 Free PMC article.

2

Small molecules from natural sources, targeting signaling pathways in diabetes.

Liu Q, Chen L, Hu L, Guo Y, Shen X. Liu Q, et al. Among authors: chen l. Biochim Biophys Acta. 2010 Oct-Dec;1799(10-12):854-65. doi: 10.1016/j.bbagrm.2010.06.004. Epub 2010 Jun 23. Biochim Biophys Acta. 2010. PMID: 20601278 Review.

3

Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.

Zhang H, Li L, Chen L, Hu L, Jiang H, Shen X. Zhang H, et al. Among authors: chen l. J Mol Biol. 2011 Mar 18;407(1):13-20. doi: 10.1016/j.jmb.2011.01.032. Epub 2011 Jan 22. J Mol Biol. 2011. PMID: 21262235

4

Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors.

Yang Q, Chen L, He X, Gao Z, Shen X, Bai D. Yang Q, et al. Among authors: chen l. Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1400-5. doi: 10.1248/cpb.56.1400. Chem Pharm Bull (Tokyo). 2008. PMID: 18827378 Free article.

5

Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling.

Han C, Zhang J, Chen L, Chen K, Shen X, Jiang H. Han C, et al. Among authors: chen k, chen l. Bioorg Med Chem. 2007 Jan 15;15(2):656-62. doi: 10.1016/j.bmc.2006.10.058. Epub 2006 Nov 1. Bioorg Med Chem. 2007. PMID: 17098431

6

(+)-Rutamarin as a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice.

Zhang Y, Zhang H, Yao XG, Shen H, Chen J, Li C, Chen L, Zheng M, Ye J, Hu L, Shen X, Jiang H. Zhang Y, et al. Among authors: chen j, chen l. PLoS One. 2012;7(2):e31811. doi: 10.1371/journal.pone.0031811. Epub 2012 Feb 27. PLoS One. 2012. PMID: 22384078 Free PMC article.

7

Enzymatic characterization and inhibitor discovery of a new cystathionine {gamma}-synthase from Helicobacter pylori.

Kong Y, Wu D, Bai H, Han C, Chen J, Chen L, Hu L, Jiang H, Shen X. Kong Y, et al. Among authors: chen j, chen l. J Biochem. 2008 Jan;143(1):59-68. doi: 10.1093/jb/mvm194. Epub 2007 Nov 1. J Biochem. 2008. PMID: 17981822

8

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: molecular modeling with biological evaluation.

Xu X, Lu Y, Chen L, Chen J, Luo X, Shen X. Xu X, et al. Among authors: chen j, chen l. Steroids. 2013 Sep;78(9):813-22. doi: 10.1016/j.steroids.2013.04.018. Epub 2013 May 23. Steroids. 2013. PMID: 23707573

9

Molecular determinants of magnolol targeting both RXRα and PPARγ.

Zhang H, Xu X, Chen L, Chen J, Hu L, Jiang H, Shen X. Zhang H, et al. Among authors: chen j, chen l. PLoS One. 2011;6(11):e28253. doi: 10.1371/journal.pone.0028253. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140563 Free PMC article.

10

Crystal structure and enzymatic characterization of thymidylate synthase X from Helicobacter pylori strain SS1.

Wang K, Wang Q, Chen J, Chen L, Jiang H, Shen X. Wang K, et al. Among authors: chen j, chen l. Protein Sci. 2011 Aug;20(8):1398-410. doi: 10.1002/pro.668. Epub 2011 Jul 6. Protein Sci. 2011. PMID: 21633987 Free PMC article.

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