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Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes.
Chen L, Pan H, Tuan TA, Teh AL, MacIsaac JL, Mah SM, McEwen LM, Li Y, Chen H, Broekman BF, Buschdorf JP, Chong YS, Kwek K, Saw SM, Gluckman PD, Fortier MV, Rifkin-Graboi A, Kobor MS, Qiu A, Meaney MJ, Holbrook JD; Gusto Study Group. Chen L, et al. Among authors: chen h. Dev Psychopathol. 2015 Feb;27(1):137-50. doi: 10.1017/S0954579414001357. Dev Psychopathol. 2015. PMID: 25640836
Transcriptome changes affecting Hedgehog and cytokine signalling in the umbilical cord: implications for disease risk.
Stünkel W, Pan H, Chew SB, Tng E, Tan JH, Chen L, Joseph R, Cheong CY, Ong ML, Lee YS, Chong YS, Saw SM, Meaney MJ, Kwek K, Sheppard AM, Gluckman PD; GUSTO Study Group; Holbrook JD. Stünkel W, et al. Among authors: chen l. PLoS One. 2012;7(7):e39744. doi: 10.1371/journal.pone.0039744. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22808055 Free PMC article.
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes.
Teh AL, Pan H, Chen L, Ong ML, Dogra S, Wong J, MacIsaac JL, Mah SM, McEwen LM, Saw SM, Godfrey KM, Chong YS, Kwek K, Kwoh CK, Soh SE, Chong MF, Barton S, Karnani N, Cheong CY, Buschdorf JP, Stünkel W, Kobor MS, Meaney MJ, Gluckman PD, Holbrook JD. Teh AL, et al. Among authors: chen l. Genome Res. 2014 Jul;24(7):1064-74. doi: 10.1101/gr.171439.113. Epub 2014 Apr 7. Genome Res. 2014. PMID: 24709820 Free PMC article.
Ethnic differences translate to inadequacy of high-risk screening for gestational diabetes mellitus in an Asian population: a cohort study.
Chong YS, Cai S, Lin H, Soh SE, Lee YS, Leow MK, Chan YH, Chen L, Holbrook JD, Tan KH, Rajadurai VS, Yeo GS, Kramer MS, Saw SM, Gluckman PD, Godfrey KM, Kwek K; GUSTO study group. Chong YS, et al. Among authors: chen l. BMC Pregnancy Childbirth. 2014 Oct 2;14:345. doi: 10.1186/1471-2393-14-345. BMC Pregnancy Childbirth. 2014. PMID: 25273851 Free PMC article.
HIF3A association with adiposity: the story begins before birth.
Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group. Pan H, et al. Among authors: chen l. Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26. Epigenomics. 2015. PMID: 26011824 Free PMC article.
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.
Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Lin X, et al. Among authors: chen l. BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1. BMC Med. 2017. PMID: 28264723 Free PMC article.
Choice of surrogate tissue influences neonatal EWAS findings.
Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N. Lin X, et al. Among authors: chen l. BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x. BMC Med. 2017. PMID: 29202839 Free PMC article.
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