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The CD8α-PILRα interaction maintains CD8+ T cell quiescence.
Zheng L, Han X, Yao S, Zhu Y, Klement J, Wu S, Ji L, Zhu G, Cheng X, Tobiasova Z, Yu W, Huang B, Vesely MD, Wang J, Zhang J, Quinlan E, Chen L. Zheng L, et al. Among authors: chen l. Science. 2022 May 27;376(6596):996-1001. doi: 10.1126/science.aaz8658. Epub 2022 May 26. Science. 2022. PMID: 35617401
Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy.
Wang J, Sun J, Liu LN, Flies DB, Nie X, Toki M, Zhang J, Song C, Zarr M, Zhou X, Han X, Archer KA, O'Neill T, Herbst RS, Boto AN, Sanmamed MF, Langermann S, Rimm DL, Chen L. Wang J, et al. Among authors: chen l. Nat Med. 2019 Apr;25(4):656-666. doi: 10.1038/s41591-019-0374-x. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833750 Free PMC article.
Myeloid cells' evasion of melanoma immunity.
Wang J, Chen L. Wang J, et al. Among authors: chen l. J Invest Dermatol. 2014 Nov;134(11):2675-2677. doi: 10.1038/jid.2014.251. J Invest Dermatol. 2014. PMID: 25318429 Free PMC article.
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