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Targeting HSPA1A in ARID2-deficient lung adenocarcinoma.
Wang X, Wang Y, Fang Z, Wang H, Zhang J, Zhang L, Huang H, Jiang Z, Jin Y, Han X, Hou S, Zhou B, Meng F, Chen L, Wong KK, Liu J, Zhang Z, Zhang X, Chen H, Sun Y, Hu L, Ji H. Wang X, et al. Among authors: chen l, chen h. Natl Sci Rev. 2021 Jan 30;8(10):nwab014. doi: 10.1093/nsr/nwab014. eCollection 2021 Oct. Natl Sci Rev. 2021. PMID: 34858604 Free PMC article.
In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.
Wu Q, Tian Y, Zhang J, Tong X, Huang H, Li S, Zhao H, Tang Y, Yuan C, Wang K, Fang Z, Gao L, Hu X, Li F, Qin Z, Yao S, Chen T, Chen H, Zhang G, Liu W, Sun Y, Chen L, Wong KK, Ge K, Chen L, Ji H. Wu Q, et al. Among authors: chen l, chen t, chen h. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3978-E3986. doi: 10.1073/pnas.1716589115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632194 Free PMC article.
Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1.
Zhao G, Gong L, Su D, Jin Y, Guo C, Yue M, Yao S, Qin Z, Ye Y, Tang Y, Wu Q, Zhang J, Cui B, Ding Q, Huang H, Hu L, Chen Y, Zhang P, Hu G, Chen L, Wong KK, Gao D, Ji H. Zhao G, et al. Among authors: chen l, chen y. J Clin Invest. 2019 Mar 1;129(3):972-987. doi: 10.1172/JCI122779. Epub 2019 Jan 28. J Clin Invest. 2019. PMID: 30688657 Free PMC article.
Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.
Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, Jin Y, Li F, Zheng C, Yang L, Deng L, Jiang Z, Jiang T, Han X, Hou S, Guo C, Li F, Gao D, Qin J, Gao D, Chen L, Lin SH, Wong KK, Li C, Hu L, Zhou C, Ji H. Wang Y, et al. Among authors: chen l. Cell Rep. 2019 Jul 9;28(2):512-525.e6. doi: 10.1016/j.celrep.2019.06.026. Cell Rep. 2019. PMID: 31291585 Free article.
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