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Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.
Broere N, Chen M, Cinar A, Singh AK, Hillesheim J, Riederer B, Lünnemann M, Rottinghaus I, Krabbenhöft A, Engelhardt R, Rausch B, Weinman EJ, Donowitz M, Hubbard A, Kocher O, de Jonge HR, Hogema BM, Seidler U. Broere N, et al. Among authors: chen m. Pflugers Arch. 2009 Mar;457(5):1079-91. doi: 10.1007/s00424-008-0579-1. Epub 2008 Aug 29. Pflugers Arch. 2009. PMID: 18758809 Free PMC article.
Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice.
Seidler U, Rottinghaus I, Hillesheim J, Chen M, Riederer B, Krabbenhöft A, Engelhardt R, Wiemann M, Wang Z, Barone S, Manns MP, Soleimani M. Seidler U, et al. Among authors: chen m. Pflugers Arch. 2008 Jan;455(4):757-66. doi: 10.1007/s00424-007-0318-z. Epub 2007 Sep 1. Pflugers Arch. 2008. PMID: 17763866
Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine.
Chen M, Sultan A, Cinar A, Yeruva S, Riederer B, Singh AK, Li J, Bonhagen J, Chen G, Yun C, Donowitz M, Hogema B, de Jonge H, Seidler U. Chen M, et al. Among authors: chen g. J Physiol. 2010 Dec 15;588(Pt 24):5049-63. doi: 10.1113/jphysiol.2010.198721. J Physiol. 2010. PMID: 20962002 Free PMC article.
Evidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitis.
Yeruva S, Chodisetti G, Luo M, Chen M, Cinar A, Ludolph L, Lünnemann M, Goldstein J, Singh AK, Riederer B, Bachmann O, Bleich A, Gereke M, Bruder D, Hagen S, He P, Yun C, Seidler U. Yeruva S, et al. Among authors: chen m. Pflugers Arch. 2015 Aug;467(8):1795-807. doi: 10.1007/s00424-014-1608-x. Epub 2014 Oct 2. Pflugers Arch. 2015. PMID: 25271043 Free PMC article.
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