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Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, Caron MG, Javitch JA, Roth BL, Jin J. Allen JA, et al. Among authors: chen m, chen x. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18488-93. doi: 10.1073/pnas.1104807108. Epub 2011 Oct 24. Proc Natl Acad Sci U S A. 2011. PMID: 22025698 Free PMC article.
Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism.
Robinson JE, Vardy E, DiBerto JF, Chefer VI, White KL, Fish EW, Chen M, Gigante E, Krouse MC, Sun H, Thorsell A, Roth BL, Heilig M, Malanga CJ. Robinson JE, et al. Among authors: chen m. Neuropsychopharmacology. 2015 Oct;40(11):2614-22. doi: 10.1038/npp.2015.109. Epub 2015 Apr 16. Neuropsychopharmacology. 2015. PMID: 25881115 Free PMC article.
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.
Welch JM, Lu J, Rodriguiz RM, Trotta NC, Peca J, Ding JD, Feliciano C, Chen M, Adams JP, Luo J, Dudek SM, Weinberg RJ, Calakos N, Wetsel WC, Feng G. Welch JM, et al. Among authors: chen m. Nature. 2007 Aug 23;448(7156):894-900. doi: 10.1038/nature06104. Nature. 2007. PMID: 17713528 Free PMC article.
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