Chen M - Search Results

1

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity.

Zhou YJ, Hanson EP, Chen YQ, Magnuson K, Chen M, Swann PG, Wange RL, Changelian PS, O'Shea JJ. Zhou YJ, et al. Among authors: chen m, chen yq. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13850-5. doi: 10.1073/pnas.94.25.13850. Proc Natl Acad Sci U S A. 1997. PMID: 9391116 Free PMC article.

2

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals.

Chen M, Cheng A, Chen YQ, Hymel A, Hanson EP, Kimmel L, Minami Y, Taniguchi T, Changelian PS, O'Shea JJ. Chen M, et al. Among authors: chen yq. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6910-5. doi: 10.1073/pnas.94.13.6910. Proc Natl Acad Sci U S A. 1997. PMID: 9192665 Free PMC article.

3

Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains.

Chen M, Cheng A, Candotti F, Zhou YJ, Hymel A, Fasth A, Notarangelo LD, O'Shea JJ. Chen M, et al. Mol Cell Biol. 2000 Feb;20(3):947-56. doi: 10.1128/MCB.20.3.947-956.2000. Mol Cell Biol. 2000. PMID: 10629052 Free PMC article.

4

Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases.

Zhou YJ, Chen M, Cusack NA, Kimmel LH, Magnuson KS, Boyd JG, Lin W, Roberts JL, Lengi A, Buckley RH, Geahlen RL, Candotti F, Gadina M, Changelian PS, O'Shea JJ. Zhou YJ, et al. Among authors: chen m. Mol Cell. 2001 Nov;8(5):959-69. doi: 10.1016/s1097-2765(01)00398-7. Mol Cell. 2001. PMID: 11741532 Free article.

5

Not just another meeting: the coming of age of JAKs and STATs.

Chen EH, Gadina M, Galon J, Chen M, O'Shea JJ. Chen EH, et al. Among authors: chen m. Immunol Today. 1998 Aug;19(8):338-41. doi: 10.1016/s0167-5699(98)01295-x. Immunol Today. 1998. PMID: 9709499 Review. No abstract available.

6

Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain.

Cacalano NA, Migone TS, Bazan F, Hanson EP, Chen M, Candotti F, O'Shea JJ, Johnston JA. Cacalano NA, et al. Among authors: chen m. EMBO J. 1999 Mar 15;18(6):1549-58. doi: 10.1093/emboj/18.6.1549. EMBO J. 1999. PMID: 10075926 Free PMC article.

7

Advances in cytokine signaling: the role of Jaks and STATs.

Chen E, Gadina M, Chen M, O'Shea JJ. Chen E, et al. Among authors: chen m. Transplant Proc. 1999 May;31(3):1482-7. doi: 10.1016/s0041-1345(99)00013-5. Transplant Proc. 1999. PMID: 10330976 Review. No abstract available.

8

Janus kinases and their role in growth and disease.

Aringer M, Cheng A, Nelson JW, Chen M, Sudarshan C, Zhou YJ, O'Shea JJ. Aringer M, et al. Among authors: chen m. Life Sci. 1999;64(24):2173-86. doi: 10.1016/s0024-3205(98)00538-4. Life Sci. 1999. PMID: 10374907 Review.

9

Characterization and analysis of the proximal Janus kinase 3 promoter.

Aringer M, Hofmann SR, Frucht DM, Chen M, Centola M, Morinobu A, Visconti R, Kastner DL, Smolen JS, O'Shea JJ. Aringer M, et al. Among authors: chen m. J Immunol. 2003 Jun 15;170(12):6057-64. doi: 10.4049/jimmunol.170.12.6057. J Immunol. 2003. PMID: 12794134

10

Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation.

Roberts JL, Lengi A, Brown SM, Chen M, Zhou YJ, O'Shea JJ, Buckley RH. Roberts JL, et al. Among authors: chen m. Blood. 2004 Mar 15;103(6):2009-18. doi: 10.1182/blood-2003-06-2104. Epub 2003 Nov 13. Blood. 2004. PMID: 14615376 Free article.

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