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21,224 results
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cGAS is essential for cellular senescence.
Yang H, Wang H, Ren J, Chen Q, Chen ZJ. Yang H, et al. Among authors: chen zj, chen q. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4612-E4620. doi: 10.1073/pnas.1705499114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533362 Free PMC article.
Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d.
Zhang B, Ye Y, Ye W, PerĨulija V, Jiang H, Chen Y, Li Y, Chen J, Lin J, Wang S, Chen Q, Han YS, Ouyang S. Zhang B, et al. Among authors: chen j, chen q, chen y. Nat Commun. 2019 Jun 11;10(1):2544. doi: 10.1038/s41467-019-10507-3. Nat Commun. 2019. PMID: 31186424 Free PMC article.
Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice.
Lai J, Fu Y, Tian S, Huang S, Luo X, Lin L, Zhang X, Wang H, Lin Z, Zhao H, Lin S, Zhao J, Xu S, Li D, Cai S, Dong L, Qian J, Liang J, Li Q, Zhang Y, Fan J, Balderas R, Chen Q. Lai J, et al. Among authors: chen q. Mol Ther. 2021 Feb 9:S1525-0016(21)00072-1. doi: 10.1016/j.ymthe.2021.02.005. Online ahead of print. Mol Ther. 2021. PMID: 33571681
Celastrol ameliorates autoimmune disorders in Trex1-deficient mice.
Liu Y, Xiao N, Du H, Kou M, Lin L, Huang M, Zhang S, Xu S, Li D, Chen Q. Liu Y, et al. Among authors: chen q. Biochem Pharmacol. 2020 Aug;178:114090. doi: 10.1016/j.bcp.2020.114090. Epub 2020 Jun 19. Biochem Pharmacol. 2020. PMID: 32565148
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