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Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.
Nandula SR, Amarnath S, Molinolo A, Bandyopadhyay BC, Hall B, Goldsmith CM, Zheng C, Larsson J, Sreenath T, Chen W, Ambudkar IS, Karlsson S, Baum BJ, Kulkarni AB. Nandula SR, et al. Among authors: chen w. Arthritis Rheum. 2007 Jun;56(6):1798-805. doi: 10.1002/art.22715. Arthritis Rheum. 2007. PMID: 17530708 Free article.
Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.
Bian Y, Terse A, Du J, Hall B, Molinolo A, Zhang P, Chen W, Flanders KC, Gutkind JS, Wakefield LM, Kulkarni AB. Bian Y, et al. Among authors: chen w. Cancer Res. 2009 Jul 15;69(14):5918-26. doi: 10.1158/0008-5472.CAN-08-4623. Epub 2009 Jul 7. Cancer Res. 2009. PMID: 19584284 Free PMC article.
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