Chen W - Search Results

1

Insulin action in the brain: cell types, circuits, and diseases.

Chen W, Cai W, Hoover B, Kahn CR. Chen W, et al. Trends Neurosci. 2022 May;45(5):384-400. doi: 10.1016/j.tins.2022.03.001. Epub 2022 Mar 28. Trends Neurosci. 2022. PMID: 35361499 Free PMC article. Review.

2

Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.

Chen W, Huang Q, Lazdon EK, Gomes A, Wong M, Stephens E, Royal TG, Frenkel D, Cai W, Kahn CR. Chen W, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2220684120. doi: 10.1073/pnas.2220684120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186836 Free PMC article.

3

Loss of Insulin Signaling in Microglia Impairs Cellular Uptake of Aβ and Neuroinflammatory Response Exacerbating Alzheimer-like Neuropathology.

Chen W, Liu X, Munoz VR, Kahn CR. Chen W, et al. bioRxiv [Preprint]. 2024 Aug 22:2024.08.22.609112. doi: 10.1101/2024.08.22.609112. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2501527122. doi: 10.1073/pnas.2501527122. PMID: 39229221 Free PMC article. Updated. Preprint.

4

Bridging brain insulin resistance to Alzheimer's pathogenesis.

Chen W, Johansen VBI, Legido-Quigley C. Chen W, et al. Trends Biochem Sci. 2024 Nov;49(11):939-941. doi: 10.1016/j.tibs.2024.09.004. Epub 2024 Oct 1. Trends Biochem Sci. 2024. PMID: 39358050

5

Insulin.

Chen W, Kahn CR. Chen W, et al. Trends Endocrinol Metab. 2025 Oct;36(10):968-969. doi: 10.1016/j.tem.2024.09.001. Epub 2024 Oct 16. Trends Endocrinol Metab. 2025. PMID: 39419674 Free PMC article. No abstract available.

6

Lrtm1: A Novel Sensor of Insulin Signaling and Regulator of Metabolism and Activity.

Yu Y, Wang G, Chen W, Liu X, Munoz VR, Cai W, Gomes AS, Kahn CR. Yu Y, et al. Among authors: chen w. Diabetes. 2025 May 1;74(5):691-704. doi: 10.2337/db24-1031. Diabetes. 2025. PMID: 39919204 Free PMC article.

7

Loss of insulin signaling in microglia impairs cellular uptake of Aβ and neuroinflammatory response exacerbating AD-like neuropathology.

Chen W, Liu X, Muñoz VR, Kahn CR. Chen W, et al. Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2501527122. doi: 10.1073/pnas.2501527122. Epub 2025 May 19. Proc Natl Acad Sci U S A. 2025. PMID: 40388612 Free PMC article.

8

Expanding the understanding of insulin resistance in brain and periphery.

Chen W, Kullmann S, Rhea EM. Chen W, et al. Trends Endocrinol Metab. 2026 Jan;37(1):17-30. doi: 10.1016/j.tem.2025.04.010. Epub 2025 May 19. Trends Endocrinol Metab. 2026. PMID: 40393910 Free PMC article. Review.

9

Disease-Associated Circular RNAs: From Biology to Computational Identification.

Tang M, Kui L, Lu G, Chen W. Tang M, et al. Among authors: chen w. Biomed Res Int. 2020 Aug 17;2020:6798590. doi: 10.1155/2020/6798590. eCollection 2020. Biomed Res Int. 2020. PMID: 32908906 Free PMC article. Review.

10

Brain insulin resistance and neuropsychiatric symptoms in Alzheimer's disease: A role for dopamine signaling.

Kontogianni A, Yang H, Chen W. Kontogianni A, et al. Among authors: chen w. Neural Regen Res. 2026 May 1;21(5):1995-1996. doi: 10.4103/NRR.NRR-D-25-00281. Epub 2025 Apr 29. Neural Regen Res. 2026. PMID: 40819304 Free PMC article. No abstract available.

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