Chen X - Search Results

1

Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells.

Chen YS, Chien CH, Goparaju CM, Hsu JT, Liang PH, Chen X. Chen YS, et al. Among authors: chen x. Protein Expr Purif. 2004 May;35(1):142-6. doi: 10.1016/j.pep.2003.12.019. Protein Expr Purif. 2004. PMID: 15039077

2

Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.

Jiaang WT, Chen YS, Hsu T, Wu SH, Chien CH, Chang CN, Chang SP, Lee SJ, Chen X. Jiaang WT, et al. Among authors: chen ys, chen x. Bioorg Med Chem Lett. 2005 Feb 1;15(3):687-91. doi: 10.1016/j.bmcl.2004.11.023. Bioorg Med Chem Lett. 2005. PMID: 15664838

3

Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.

Lee HJ, Chen YS, Chou CY, Chien CH, Lin CH, Chang GG, Chen X. Lee HJ, et al. Among authors: chen ys, chen x. J Biol Chem. 2006 Dec 15;281(50):38653-62. doi: 10.1074/jbc.M603895200. Epub 2006 Oct 13. J Biol Chem. 2006. PMID: 17040910 Free article.

4

One site mutation disrupts dimer formation in human DPP-IV proteins.

Chien CH, Huang LH, Chou CY, Chen YS, Han YS, Chang GG, Liang PH, Chen X. Chien CH, et al. Among authors: chen ys, chen x. J Biol Chem. 2004 Dec 10;279(50):52338-45. doi: 10.1074/jbc.M406185200. Epub 2004 Sep 24. J Biol Chem. 2004. PMID: 15448155 Free article.

5

Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.

Lu IL, Lee SJ, Tsu H, Wu SY, Kao KH, Chien CH, Chang YY, Chen YS, Cheng JH, Chang CN, Chen TW, Chang SP, Chen X, Jiaang WT. Lu IL, et al. Among authors: chen tw, chen ys, chen x. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3271-5. doi: 10.1016/j.bmcl.2005.04.051. Bioorg Med Chem Lett. 2005. PMID: 15927466

6

2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV.

Tsu H, Chen X, Chen CT, Lee SJ, Chang CN, Kao KH, Coumar MS, Yeh YT, Chien CH, Wang HS, Lin KT, Chang YY, Wu SH, Chen YS, Lu IL, Wu SY, Tsai TY, Chen WC, Hsieh HP, Chao YS, Jiaang WT. Tsu H, et al. Among authors: chen ct, chen wc, chen x, chen ys. J Med Chem. 2006 Jan 12;49(1):373-80. doi: 10.1021/jm0507781. J Med Chem. 2006. PMID: 16392822

7

Identification of hydrophobic residues critical for DPP-IV dimerization.

Chien CH, Tsai CH, Lin CH, Chou CY, Chen X. Chien CH, et al. Among authors: chen x. Biochemistry. 2006 Jun 13;45(23):7006-12. doi: 10.1021/bi060401c. Biochemistry. 2006. PMID: 16752891

8

Biochemical properties and expression profile of human prolyl dipeptidase DPP9.

Tang HK, Tang HY, Hsu SC, Chu YR, Chien CH, Shu CH, Chen X. Tang HK, et al. Among authors: chen x. Arch Biochem Biophys. 2009 May 15;485(2):120-7. doi: 10.1016/j.abb.2009.02.015. Epub 2009 Mar 5. Arch Biochem Biophys. 2009. PMID: 19268648

9

Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor.

Wu JJ, Tang HK, Yeh TK, Chen CM, Shy HS, Chu YR, Chien CH, Tsai TY, Huang YC, Huang YL, Huang CH, Tseng HY, Jiaang WT, Chao YS, Chen X. Wu JJ, et al. Among authors: chen cm, chen x. Biochem Pharmacol. 2009 Jul 15;78(2):203-10. doi: 10.1016/j.bcp.2009.03.032. Epub 2009 Apr 11. Biochem Pharmacol. 2009. PMID: 19439267

10

Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate.

Huang CH, Suen CS, Lin CT, Chien CH, Lee HY, Chung KM, Tsai TY, Jiaang WT, Hwang MJ, Chen X. Huang CH, et al. Among authors: chen x. J Biochem. 2011 Jun;149(6):685-92. doi: 10.1093/jb/mvr017. Epub 2011 Feb 1. J Biochem. 2011. PMID: 21288888

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