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66,042 results
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The effect of Fc glycan forms on human IgG2 antibody clearance in humans.
Chen X, Liu YD, Flynn GC. Chen X, et al. Glycobiology. 2009 Mar;19(3):240-9. doi: 10.1093/glycob/cwn120. Epub 2008 Oct 30. Glycobiology. 2009. PMID: 18974198
Analysis of N-glycans from recombinant immunoglobulin G by on-line reversed-phase high-performance liquid chromatography/mass spectrometry.
Chen X, Flynn GC. Chen X, et al. Anal Biochem. 2007 Nov 15;370(2):147-61. doi: 10.1016/j.ab.2007.08.012. Epub 2007 Aug 14. Anal Biochem. 2007. PMID: 17880905
Gas-phase oligosaccharide nonreducing end (GONE) sequencing and structural analysis by reversed phase HPLC/mass spectrometry with polarity switching.
Chen X, Flynn GC. Chen X, et al. J Am Soc Mass Spectrom. 2009 Oct;20(10):1821-33. doi: 10.1016/j.jasms.2009.06.003. Epub 2009 Jun 25. J Am Soc Mass Spectrom. 2009. PMID: 19631557
Naturally occurring glycan forms of human immunoglobulins G1 and G2.
Flynn GC, Chen X, Liu YD, Shah B, Zhang Z. Flynn GC, et al. Among authors: chen x. Mol Immunol. 2010 Jul;47(11-12):2074-82. doi: 10.1016/j.molimm.2010.04.006. Epub 2010 May 4. Mol Immunol. 2010. PMID: 20444501
A high throughput dimer screening assay for monoclonal antibodies using chemical cross-linking and microchip electrophoresis.
Chen X, Flynn GC. Chen X, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 1;877(27):3012-8. doi: 10.1016/j.jchromb.2009.07.020. Epub 2009 Jul 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19646934
Microchip assays for screening monoclonal antibody product quality.
Chen X, Tang K, Lee M, Flynn GC. Chen X, et al. Electrophoresis. 2008 Dec;29(24):4993-5002. doi: 10.1002/elps.200800324. Electrophoresis. 2008. PMID: 19130579
Human IgG2 antibody disulfide rearrangement in vivo.
Liu YD, Chen X, Enk JZ, Plant M, Dillon TM, Flynn GC. Liu YD, et al. Among authors: chen x. J Biol Chem. 2008 Oct 24;283(43):29266-72. doi: 10.1074/jbc.M804787200. Epub 2008 Aug 19. J Biol Chem. 2008. PMID: 18713741 Free PMC article.
Mass spectrometry for structural characterization of therapeutic antibodies.
Zhang Z, Pan H, Chen X. Zhang Z, et al. Among authors: chen x. Mass Spectrom Rev. 2009 Jan-Feb;28(1):147-76. doi: 10.1002/mas.20190. Mass Spectrom Rev. 2009. PMID: 18720354 Review.
A new tool for monoclonal antibody analysis: application of IdeS proteolysis in IgG domain-specific characterization.
An Y, Zhang Y, Mueller HM, Shameem M, Chen X. An Y, et al. Among authors: chen x. MAbs. 2014 Jul-Aug;6(4):879-93. doi: 10.4161/mabs.28762. MAbs. 2014. PMID: 24927271 Free PMC article.
Admission hyperglycemia as an independent predictor of long-term prognosis in non-diabetic patients with acute myocardial infarction: a retrospective study.
Cui CY, Zhou MG, Cheng LC, Ye T, Zhang YM, Zhu F, Li SY, Jiang XL, Chen Q, Qi LY, Chen X, Yang SQ, Cai L. Cui CY, et al. Among authors: chen x. J Diabetes Investig. 2020 Nov 28. doi: 10.1111/jdi.13468. Online ahead of print. J Diabetes Investig. 2020. PMID: 33249775
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