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Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Chen X, Wang Q, Ni F, Ma J. Chen X, et al. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11352-7. doi: 10.1073/pnas.1000142107. Epub 2010 Jun 3. Proc Natl Acad Sci U S A. 2010. PMID: 20534430 Free PMC article.
In this study, by applying a novel normal-mode-based X-ray crystallographic refinement method to the original diffraction data and structural model, we established the structure of full-length Kv1.2 in its native form. ...
In this study, by applying a novel normal-mode-based X-ray crystallographic refinement method to the original diffraction data and st …
Structural basis of actin filament nucleation by tandem W domains.
Chen X, Ni F, Tian X, Kondrashkina E, Wang Q, Ma J. Chen X, et al. Cell Rep. 2013 Jun 27;3(6):1910-20. doi: 10.1016/j.celrep.2013.04.028. Epub 2013 May 30. Cell Rep. 2013. PMID: 23727244 Free PMC article.
Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement.
Chen X, Lu M, Poon BK, Wang Q, Ma J. Chen X, et al. Acta Crystallogr D Biol Crystallogr. 2009 Apr;65(Pt 4):339-47. doi: 10.1107/S0907444909003539. Epub 2009 Mar 19. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19307715 Free PMC article.
These results further underscore the effectiveness of this normal-mode-based method in improving models of protein and nonprotein components in low-resolution X-ray structures....
These results further underscore the effectiveness of this normal-mode-based method in improving models of protein and nonprotein components …
Structural basis for receptor specificity of influenza B virus hemagglutinin.
Wang Q, Tian X, Chen X, Ma J. Wang Q, et al. Among authors: chen x. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16874-9. doi: 10.1073/pnas.0708363104. Epub 2007 Oct 17. Proc Natl Acad Sci U S A. 2007. PMID: 17942670 Free PMC article.
Normal mode refinement of anisotropic thermal parameters for a supramolecular complex at 3.42-A crystallographic resolution.
Poon BK, Chen X, Lu M, Vyas NK, Quiocho FA, Wang Q, Ma J. Poon BK, et al. Among authors: chen x. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7869-74. doi: 10.1073/pnas.0701204104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470791 Free PMC article.
Here we report a normal-mode-based protocol for modeling anisotropic thermal motions of proteins in x-ray crystallographic refinement. ...This normal-mode-based refinement is an effective way of describing anisotropic thermal motions in x-ray structures and is parti …
Here we report a normal-mode-based protocol for modeling anisotropic thermal motions of proteins in x-ray crystallographic refinement …
Normal-mode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 A crystallographic resolution.
Chen X, Poon BK, Dousis A, Wang Q, Ma J. Chen X, et al. Structure. 2007 Aug;15(8):955-62. doi: 10.1016/j.str.2007.06.012. Structure. 2007. PMID: 17698000 Free PMC article.
Thus, a small set of modes is sufficient to represent the anisotropic thermal motions in X-ray crystallographic refinement. By applying the method to potassium channel KcsA at 3.2 A, we obtained a structural model with an improved fit with the diffraction data. ...
Thus, a small set of modes is sufficient to represent the anisotropic thermal motions in X-ray crystallographic refinement. By applyi …
Structural insights into the membrane fusion mechanism mediated by influenza virus hemagglutinin.
Ni F, Chen X, Shen J, Wang Q. Ni F, et al. Among authors: chen x. Biochemistry. 2014 Feb 11;53(5):846-54. doi: 10.1021/bi401525h. Epub 2014 Jan 28. Biochemistry. 2014. PMID: 24433110 Free PMC article.
Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells.
Chen X, Ni F, Kondrashkina E, Ma J, Wang Q. Chen X, et al. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12687-92. doi: 10.1073/pnas.1512464112. Epub 2015 Sep 28. Proc Natl Acad Sci U S A. 2015. PMID: 26417072 Free PMC article.
Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein.
Xie Q, Wang Z, Ni F, Chen X, Ma J, Patel N, Lu H, Liu Y, Tian JH, Flyer D, Massare MJ, Ellingsworth L, Glenn G, Smith G, Wang Q. Xie Q, et al. Among authors: chen x. PLoS One. 2019 Feb 7;14(2):e0210749. doi: 10.1371/journal.pone.0210749. eCollection 2019. PLoS One. 2019. PMID: 30730999 Free PMC article.
Reprogramming progressive cells display low CAG promoter activity.
Hu X, Wu Q, Zhang J, Kim J, Chen X, Hartman AA, Eastman AE, Park IH, Guo S. Hu X, et al. Among authors: chen x. Stem Cells. 2020 Oct 19. doi: 10.1002/stem.3295. Online ahead of print. Stem Cells. 2020. PMID: 33075202
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