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PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Moreno-Fernandez ME, Giles DA, Oates JR, Chan CC, Damen MSMA, Doll JR, Stankiewicz TE, Chen X, Chetal K, Karns R, Weirauch MT, Romick-Rosendale L, Xanthakos SA, Sheridan R, Szabo S, Shah AS, Helmrath MA, Inge TH, Deshmukh H, Salomonis N, Divanovic S. Moreno-Fernandez ME, et al. Among authors: chen x. Cell Metab. 2021 Jun 1;33(6):1187-1204.e9. doi: 10.1016/j.cmet.2021.04.018. Epub 2021 May 17. Cell Metab. 2021. PMID: 34004162 Free PMC article.
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network.
Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. Fang J, et al. Among authors: chen x. Cell Rep. 2014 Sep 11;8(5):1328-38. doi: 10.1016/j.celrep.2014.07.062. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199827 Free PMC article.
Determination and inference of eukaryotic transcription factor sequence specificity.
Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, Walhout AJM, Bouget FY, Ratsch G, Larrondo LF, Ecker JR, Hughes TR. Weirauch MT, et al. Among authors: chen x. Cell. 2014 Sep 11;158(6):1431-1443. doi: 10.1016/j.cell.2014.08.009. Cell. 2014. PMID: 25215497 Free PMC article.
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.
Ballester B, Medina-Rivera A, Schmidt D, Gonzàlez-Porta M, Carlucci M, Chen X, Chessman K, Faure AJ, Funnell AP, Goncalves A, Kutter C, Lukk M, Menon S, McLaren WM, Stefflova K, Watt S, Weirauch MT, Crossley M, Marioni JC, Odom DT, Flicek P, Wilson MD. Ballester B, et al. Among authors: chen x. Elife. 2014 Oct 3;3:e02626. doi: 10.7554/eLife.02626. Elife. 2014. PMID: 25279814 Free PMC article.
MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis.
Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y, Tang Y, Weirauch MT, Chen X, Zhu W, Wang Y, Chen B, Qian Y, Chen Y, Fang J, Herbst R, Richman L, Jallal B, Harley JB, Flavell RA, Yao Y, Shen N. Pan W, et al. Among authors: chen b, chen x, chen y. Nat Commun. 2015 May 12;6:7096. doi: 10.1038/ncomms8096. Nat Commun. 2015. PMID: 25963922 Free article.
Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis.
Bouffi C, Kartashov AV, Schollaert KL, Chen X, Bacon WC, Weirauch MT, Barski A, Fulkerson PC. Bouffi C, et al. Among authors: chen x. J Immunol. 2015 Sep 15;195(6):2683-95. doi: 10.4049/jimmunol.1500510. Epub 2015 Aug 12. J Immunol. 2015. PMID: 26268651 Free PMC article.
Multiple layers of transcriptional regulation by PLZF in NKT-cell development.
Mao AP, Constantinides MG, Mathew R, Zuo Z, Chen X, Weirauch MT, Bendelac A. Mao AP, et al. Among authors: chen x. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7602-7. doi: 10.1073/pnas.1601504113. Epub 2016 Jun 20. Proc Natl Acad Sci U S A. 2016. PMID: 27325774 Free PMC article.
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